Gene description for Dpep2
Gene name dipeptidase 2
Gene symbol Dpep2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Dpep2
ExoCarta ExoCarta_291984
Vesiclepedia VP_291984
Entrez Gene 291984
UniProt Q5M872  
 Dpep2 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Dpep2
Molecular Function
    exopeptidase activity GO:0008238 ISO
    dipeptidase activity GO:0016805 ISO
    dipeptidase activity GO:0016805 ISS
    metal ion binding GO:0046872 IEA
    metallodipeptidase activity GO:0070573 IEA
Biological Process
    proteolysis GO:0006508 IEA
    leukotriene metabolic process GO:0006691 ISO
    leukotriene metabolic process GO:0006691 ISS
    leukotriene D4 catabolic process GO:1901749 IEA
    leukotriene D4 catabolic process GO:1901749 ISO
    leukotriene D4 catabolic process GO:1901749 ISS
Subcellular Localization
    membrane GO:0016020 ISO
    membrane GO:0016020 ISS
    side of membrane GO:0098552 IEA
 Experiment description of studies that identified Dpep2 in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Dpep2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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