Gene description for Kars
Gene name lysyl-tRNA synthetase
Gene symbol Kars
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Kars
ExoCarta ExoCarta_292028
Entrez Gene 292028
 Kars identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Kars
Molecular Function
    lysine-tRNA ligase activity GO:0004824 ISO
    ATP binding GO:0005524 IDA
    tRNA binding GO:0000049 IDA
    amino acid binding GO:0016597 IDA
Biological Process
    diadenosine tetraphosphate biosynthetic process GO:0015966 IDA
    lysyl-tRNA aminoacylation GO:0006430 ISO
Subcellular Localization
    aminoacyl-tRNA synthetase multienzyme complex GO:0017101 IDA
    microtubule cytoskeleton GO:0015630 ISO
    mitochondrion GO:0005739 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Kars in exosomes
Experiment ID 95
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Kars
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Kars is involved
No pathways found

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