Gene description for Kars
Gene name	lysyl-tRNA synthetase
Gene symbol	Kars
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Kars
ExoCarta	ExoCarta_292028
Vesiclepedia	VP_292028
Entrez Gene	292028
Kars identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Kars

Molecular Function     tRNA binding GO:0000049 IBA     tRNA binding GO:0000049 IDA     nucleic acid binding GO:0003676 IEA     ATP:ADP adenylyltransferase activity GO:0003877 IBA     ATP:ADP adenylyltransferase activity GO:0003877 ISO     ATP:ADP adenylyltransferase activity GO:0003877 ISS     lysine-tRNA ligase activity GO:0004824 IBA     lysine-tRNA ligase activity GO:0004824 IDA     lysine-tRNA ligase activity GO:0004824 IEA     lysine-tRNA ligase activity GO:0004824 ISO     ATP binding GO:0005524 IDA     ATP binding GO:0005524 IEA     amino acid binding GO:0016597 IDA     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 ISO     scaffold protein binding GO:0097110 ISO Biological Process     basophil activation involved in immune response GO:0002276 IBA     basophil activation involved in immune response GO:0002276 IMP     basophil activation involved in immune response GO:0002276 ISO     positive regulation of inflammatory response to antigenic stimulus GO:0002863 ISO     lysyl-tRNA aminoacylation GO:0006430 IBA     lysyl-tRNA aminoacylation GO:0006430 IDA     lysyl-tRNA aminoacylation GO:0006430 IEA     lysyl-tRNA aminoacylation GO:0006430 ISO     response to X-ray GO:0010165 IDA     diadenosine tetraphosphate biosynthetic process GO:0015966 IBA     diadenosine tetraphosphate biosynthetic process GO:0015966 IDA     diadenosine tetraphosphate biosynthetic process GO:0015966 IMP     diadenosine tetraphosphate biosynthetic process GO:0015966 ISO     positive regulation of macrophage activation GO:0043032 IBA     positive regulation of macrophage activation GO:0043032 ISO     positive regulation of DNA-templated transcription GO:0045893 IMP     positive regulation of DNA-templated transcription GO:0045893 ISO     ERK1 and ERK2 cascade GO:0070371 IMP     ERK1 and ERK2 cascade GO:0070371 ISO Subcellular Localization     extracellular space GO:0005615 ISO     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 IEA     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 ISO     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     aminoacyl-tRNA synthetase multienzyme complex GO:0017101 IBA     aminoacyl-tRNA synthetase multienzyme complex GO:0017101 IDA     aminoacyl-tRNA synthetase multienzyme complex GO:0017101 ISO