Gene description for Arg1
Gene name	arginase 1
Gene symbol	Arg1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Arg1
ExoCarta	ExoCarta_29221
Vesiclepedia	VP_29221
Entrez Gene	29221
UniProt	P07824
Arg1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Arg1

Molecular Function     arginase activity GO:0004053 IBA     arginase activity GO:0004053 IDA     arginase activity GO:0004053 IEA     arginase activity GO:0004053 ISO     manganese ion binding GO:0030145 IBA     manganese ion binding GO:0030145 IDA     identical protein binding GO:0042802 IPI     metal ion binding GO:0046872 IEA Biological Process     urea cycle GO:0000050 IDA     urea cycle GO:0000050 IEA     liver development GO:0001889 IEP     positive regulation of endothelial cell proliferation GO:0001938 IDA     adaptive immune response GO:0002250 IEA     arginine metabolic process GO:0006525 IDA     arginine metabolic process GO:0006525 IEA     female pregnancy GO:0007565 IEP     response to xenobiotic stimulus GO:0009410 IEP     response to nematode GO:0009624 IEA     response to nematode GO:0009624 ISO     response to herbicide GO:0009635 IEP     response to manganese ion GO:0010042 IEP     response to zinc ion GO:0010043 IEP     response to selenium ion GO:0010269 IEP     response to amine GO:0014075 IEP     arginine catabolic process to ornithine GO:0019547 IBA     arginine catabolic process to ornithine GO:0019547 IDA     lung development GO:0030324 IEP     response to lipopolysaccharide GO:0032496 IEP     collagen biosynthetic process GO:0032964 IMP     response to vitamin A GO:0033189 IEP     response to vitamin E GO:0033197 IEP     negative regulation of T cell proliferation GO:0042130 ISO     defense response to protozoan GO:0042832 IEA     defense response to protozoan GO:0042832 ISO     response to amino acid GO:0043200 IEP     response to peptide hormone GO:0043434 IEP     innate immune response GO:0045087 IEA     negative regulation of activated T cell proliferation GO:0046007 IEA     negative regulation of activated T cell proliferation GO:0046007 ISO     response to cadmium ion GO:0046686 IEP     response to steroid hormone GO:0048545 IEP     response to axon injury GO:0048678 IEP     response to methylmercury GO:0051597 IEP     mammary gland involution GO:0060056 IEP     maternal process involved in female pregnancy GO:0060135 IEP     negative regulation of type II interferon-mediated signaling pathway GO:0060336 IEA     negative regulation of type II interferon-mediated signaling pathway GO:0060336 ISO     cellular response to hydrogen peroxide GO:0070301 IEP     positive regulation of neutrophil mediated killing of fungus GO:0070965 IEA     positive regulation of neutrophil mediated killing of fungus GO:0070965 ISO     cellular response to lipopolysaccharide GO:0071222 IEP     cellular response to interleukin-4 GO:0071353 IEP     cellular response to glucagon stimulus GO:0071377 IEP     cellular response to dexamethasone stimulus GO:0071549 IEP     cellular response to transforming growth factor beta stimulus GO:0071560 IEP     regulation of L-arginine import across plasma membrane GO:1905541 IDA     negative regulation of T-helper 2 cell cytokine production GO:2000552 IEA     negative regulation of T-helper 2 cell cytokine production GO:2000552 ISO Subcellular Localization     extracellular space GO:0005615 IDA     extracellular space GO:0005615 IEA     extracellular space GO:0005615 ISO     cytoplasm GO:0005737 IBA     mitochondrial outer membrane GO:0005741 IDA     cytosol GO:0005829 IBA     neuronal cell body GO:0043025 IDA