Gene description for Nccrp1
Gene name non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
Gene symbol Nccrp1
Other names/aliases RGD1305932
Species Rattus norvegicus
 Database cross references - Nccrp1
ExoCarta ExoCarta_292755
Vesiclepedia VP_292755
Entrez Gene 292755
 Nccrp1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Nccrp1
Molecular Function
    ubiquitin protein ligase activity GO:0061630 IBA
Biological Process
    glycoprotein catabolic process GO:0006516 IBA
    positive regulation of cell population proliferation GO:0008284 ISO
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146 IBA
    ERAD pathway GO:0036503 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    SCF ubiquitin ligase complex GO:0019005 IBA
 Experiment description of studies that identified Nccrp1 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Nccrp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mib1  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Nccrp1 is involved
No pathways found





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