Gene description for Pepd
Gene name peptidase D
Gene symbol Pepd
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Pepd
ExoCarta ExoCarta_292808
Entrez Gene 292808
UniProt Q5I0D7  
 Pepd identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Pepd
Molecular Function
    metallopeptidase activity GO:0008237 IEA
    aminopeptidase activity GO:0004177 IEA
    dipeptidase activity GO:0016805 IEA
    peptidase activity GO:0008233 ISO
    manganese ion binding GO:0030145 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    proteolysis GO:0006508 ISO
    collagen catabolic process GO:0030574 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Pepd in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Pepd
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pepd is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here