Gene description for Clec11a
Gene name C-type lectin domain family 11, member A
Gene symbol Clec11a
Other names/aliases Scgf
Species Rattus norvegicus
 Database cross references - Clec11a
ExoCarta ExoCarta_29313
Vesiclepedia VP_29313
Entrez Gene 29313
UniProt O88201  
 Clec11a identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Clec11a
Molecular Function
    growth factor activity GO:0008083 IBA
    growth factor activity GO:0008083 ISO
    growth factor activity GO:0008083 ISS
    carbohydrate binding GO:0030246 IEA
    carbohydrate binding GO:0030246 NAS
Biological Process
    ossification GO:0001503 IBA
    signal transduction GO:0007165 IEA
    positive regulation of cell population proliferation GO:0008284 ISO
    positive regulation of cell population proliferation GO:0008284 ISS
Subcellular Localization
    extracellular region GO:0005576 ISO
    extracellular region GO:0005576 ISS
    extracellular space GO:0005615 IBA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Clec11a in sEVs
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Clec11a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Clec11a is involved
No pathways found





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