Gene description for Slc6a18
Gene name solute carrier family 6 (neutral amino acid transporter), member 18
Gene symbol Slc6a18
Other names/aliases Rosit
Xtrp2
Species Rattus norvegicus
 Database cross references - Slc6a18
ExoCarta ExoCarta_29323
Vesiclepedia VP_29323
Entrez Gene 29323
UniProt Q62687  
 Slc6a18 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Slc6a18
Molecular Function
    neurotransmitter:sodium symporter activity GO:0005328 IEA
Biological Process
    neurotransmitter transport GO:0006836 IEA
    transmembrane transport GO:0055085 IEA
    response to osmotic stress GO:0006970 IEP
    amino acid transport GO:0006865 IEA
    amino acid transmembrane transport GO:0003333 ISO
    hyperosmotic response GO:0006972 NAS
Subcellular Localization
    brush border membrane GO:0031526 ISO
    plasma membrane GO:0005886 ISO
    integral component of plasma membrane GO:0005887 IEA
 Experiment description of studies that identified Slc6a18 in exosomes
1
Experiment ID 192
MISEV standards
CEM
EV Biophysical techniques
TSG101|HSP70|CD63|CD81|FLOT
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Slc6a18
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc6a18 is involved
No pathways found





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