Gene description for Hras
Gene name	Harvey rat sarcoma virus oncogene
Gene symbol	Hras
Other names/aliases	HRAS1 c-H-ras
Species	Rattus norvegicus
Database cross references - Hras
ExoCarta	ExoCarta_293621
Entrez Gene	293621
UniProt	P20171
Hras identified in exosomes derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Hras

Molecular Function     GTP binding GO:0005525 ISS     protein C-terminus binding GO:0008022 ISO     protein binding GO:0005515 IPI Biological Process     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     regulation of long-term neuronal synaptic plasticity GO:0048169 ISO     negative regulation of cell proliferation GO:0008285 ISO     striated muscle cell differentiation GO:0051146 IEA     negative regulation of gene expression GO:0010629 ISO     positive regulation of actin cytoskeleton reorganization GO:2000251 ISO     positive regulation of JNK cascade GO:0046330 ISO     cell cycle arrest GO:0007050 ISO     positive regulation of Ras protein signal transduction GO:0046579 IMP     positive regulation of DNA replication GO:0045740 ISO     negative regulation of cell differentiation GO:0045596 IEA     positive regulation of cell migration GO:0030335 ISO     social behavior GO:0035176 IEP     positive regulation of gene expression GO:0010628 ISO     positive regulation of epithelial cell proliferation GO:0050679 ISO     positive regulation of MAP kinase activity GO:0043406 ISO     positive regulation of Rac protein signal transduction GO:0035022 IEA     epithelial tube branching involved in lung morphogenesis GO:0060441 IEA     positive regulation of miRNA metabolic process GO:2000630 ISO     regulation of synaptic transmission, GABAergic GO:0032228 IEA     intrinsic apoptotic signaling pathway GO:0097193 ISO     actin cytoskeleton organization GO:0030036 IEA     endocytosis GO:0006897 ISO     positive regulation of MAPK cascade GO:0043410 ISO     Ras protein signal transduction GO:0007265 ISO     mitotic cell cycle checkpoint GO:0007093 ISO     apoptotic process GO:0006915 IMP     positive regulation of wound healing GO:0090303 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     negative regulation of GTPase activity GO:0034260 ISO     positive regulation of cell proliferation GO:0008284 ISO     visual learning GO:0008542 IEA     cellular senescence GO:0090398 ISO     positive regulation of ruffle assembly GO:1900029 ISO     protein heterooligomerization GO:0051291 IPI     positive regulation of protein phosphorylation GO:0001934 ISO     cell aging GO:0007569 ISO     positive regulation of GTPase activity GO:0043547 ISO     cell proliferation GO:0008283 ISO     small GTPase mediated signal transduction GO:0007264 ISO Subcellular Localization     intracellular membrane-bounded organelle GO:0043231 IDA     intracellular GO:0005622 ISO     plasma membrane GO:0005886 TAS     Golgi apparatus GO:0005794 ISS     Golgi membrane GO:0000139 IEA