Gene description for Hras
Gene name	Harvey rat sarcoma virus oncogene
Gene symbol	Hras
Other names/aliases	HRAS1 c-H-ras
Species	Rattus norvegicus
Database cross references - Hras
ExoCarta	ExoCarta_293621
Vesiclepedia	VP_293621
Entrez Gene	293621
UniProt	P20171
Hras identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Hras

Molecular Function     GTPase activity GO:0003924 IBA     GTPase activity GO:0003924 IEA     GTPase activity GO:0003924 ISO     G protein activity GO:0003925 IEA     protein binding GO:0005515 IPI     GTP binding GO:0005525 IBA     GTP binding GO:0005525 IEA     GTP binding GO:0005525 ISO     GTP binding GO:0005525 ISS     GDP binding GO:0019003 IBA     GDP binding GO:0019003 ISO     protein-membrane adaptor activity GO:0043495 ISO     protein-containing complex binding GO:0044877 IPI     phospholipase C activator activity GO:0160185 ISO Biological Process     liver development GO:0001889 IEP     positive regulation of protein phosphorylation GO:0001934 ISO     regulation of transcription by RNA polymerase II GO:0006357 ISO     endocytosis GO:0006897 ISO     signal transduction GO:0007165 IEA     small GTPase-mediated signal transduction GO:0007264 ISO     Ras protein signal transduction GO:0007265 IBA     Ras protein signal transduction GO:0007265 IMP     Ras protein signal transduction GO:0007265 ISO     positive regulation of cell population proliferation GO:0008284 ISO     positive regulation of cell population proliferation GO:0008284 ISO     negative regulation of cell population proliferation GO:0008285 ISO     insulin receptor signaling pathway GO:0008286 ISO     positive regulation of gene expression GO:0010628 ISO     negative regulation of gene expression GO:0010629 ISO     Schwann cell development GO:0014044 ISO     positive regulation of cell migration GO:0030335 ISO     positive regulation of type II interferon production GO:0032729 ISO     regulation of actin cytoskeleton organization GO:0032956 ISO     negative regulation of GTPase activity GO:0034260 ISO     response to isolation stress GO:0035900 IEP     T-helper 1 type immune response GO:0042088 ISO     regulation of cell population proliferation GO:0042127 ISO     myelination GO:0042552 ISO     defense response to protozoan GO:0042832 ISO     positive regulation of MAP kinase activity GO:0043406 ISO     positive regulation of MAPK cascade GO:0043410 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     positive regulation of GTPase activity GO:0043547 ISO     positive regulation of DNA replication GO:0045740 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     positive regulation of JNK cascade GO:0046330 ISO     positive regulation of Ras protein signal transduction GO:0046579 IMP     fibroblast proliferation GO:0048144 ISO     positive regulation of fibroblast proliferation GO:0048146 ISO     regulation of long-term neuronal synaptic plasticity GO:0048169 ISO     positive regulation of epithelial cell proliferation GO:0050679 ISO     T cell receptor signaling pathway GO:0050852 ISO     neuron apoptotic process GO:0051402 ISO     regulation of cell cycle GO:0051726 ISO     adipose tissue development GO:0060612 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 IMP     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     cellular response to gamma radiation GO:0071480 ISO     positive regulation of wound healing GO:0090303 ISO     positive regulation of protein targeting to membrane GO:0090314 ISO     cellular senescence GO:0090398 IBA     cellular senescence GO:0090398 IEP     cellular senescence GO:0090398 ISO     cellular senescence GO:0090398 ISO     oncogene-induced cell senescence GO:0090402 ISO     intrinsic apoptotic signaling pathway GO:0097193 ISO     regulation of neurotransmitter receptor localization to postsynaptic specialization membrane GO:0098696 ISO     positive regulation of ruffle assembly GO:1900029 ISO     positive regulation of miRNA metabolic process GO:2000630 ISO Subcellular Localization     Golgi membrane GO:0000139 IEA     nucleoplasm GO:0005654 ISO     Golgi apparatus GO:0005794 ISO     Golgi apparatus GO:0005794 ISS     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 TAS     glutamatergic synapse GO:0098978 ISO     GTPase complex GO:1905360 ISO