Gene description for Ubxn1
Gene name UBX domain protein 1
Gene symbol Ubxn1
Other names/aliases 2B28
RGD1309471
Species Rattus norvegicus
 Database cross references - Ubxn1
ExoCarta ExoCarta_293719
Entrez Gene 293719
 Ubxn1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ubxn1
Molecular Function
    ubiquitin binding GO:0043130 ISO
    polyubiquitin binding GO:0031593 ISO
    ubiquitin protein ligase binding GO:0031625 ISO
    K6-linked polyubiquitin binding GO:0071796 ISS
    protein binding GO:0005515 IPI
    ATPase binding GO:0051117 ISO
Biological Process
    negative regulation of protein ubiquitination GO:0031397 ISS
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 ISS
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 ISO
    VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 ISO
    proteasome complex GO:0000502 ISO
    neuronal cell body GO:0043025 IDA
    dendrite GO:0030425 IDA
 Experiment description of studies that identified Ubxn1 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ubxn1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ubxn1 is involved
No pathways found





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