Gene description for Ubl4a
Gene name ubiquitin-like 4A
Gene symbol Ubl4a
Other names/aliases RGD1563983
Ubl4
Species Rattus norvegicus
 Database cross references - Ubl4a
ExoCarta ExoCarta_293864
Vesiclepedia VP_293864
Entrez Gene 293864
UniProt B2GV38  
 Ubl4a identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Ubl4a
Molecular Function
    protein binding GO:0005515 IPI
    protein-folding chaperone binding GO:0051087 IBA
    protein-folding chaperone binding GO:0051087 IEA
    protein-folding chaperone binding GO:0051087 ISO
Biological Process
    ubiquitin-dependent protein catabolic process GO:0006511 IEA
    ubiquitin-dependent protein catabolic process GO:0006511 ISO
    post-translational protein targeting to endoplasmic reticulum membrane GO:0006620 IBA
    post-translational protein targeting to endoplasmic reticulum membrane GO:0006620 IEA
    post-translational protein targeting to endoplasmic reticulum membrane GO:0006620 ISO
    regulation of protein stability GO:0031647 IEA
    regulation of protein stability GO:0031647 ISO
    tail-anchored membrane protein insertion into ER membrane GO:0071816 IBA
    tail-anchored membrane protein insertion into ER membrane GO:0071816 IEA
    tail-anchored membrane protein insertion into ER membrane GO:0071816 ISO
    tail-anchored membrane protein insertion into ER membrane GO:0071816 ISS
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
    membrane GO:0016020 IEA
    membrane GO:0016020 ISO
    BAT3 complex GO:0071818 IBA
    BAT3 complex GO:0071818 IEA
    BAT3 complex GO:0071818 ISO
    BAT3 complex GO:0071818 ISS
 Experiment description of studies that identified Ubl4a in sEVs
1
Experiment ID 98
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Ubl4a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ubl4a is involved
No pathways found





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