Gene description for Skiv2l
Gene name superkiller viralicidic activity 2-like (S. cerevisiae)
Gene symbol Skiv2l
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Skiv2l
ExoCarta ExoCarta_294260
Vesiclepedia VP_294260
Entrez Gene 294260
 Skiv2l identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Skiv2l
Molecular Function
    RNA binding GO:0003723 IEA
    RNA helicase activity GO:0003724 IBA
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
    3'-5' RNA helicase activity GO:0034458 ISO
Biological Process
    nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay GO:0070478 IBA
    nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay GO:0070478 ISO
    rescue of stalled ribosome GO:0072344 ISO
Subcellular Localization
    Ski complex GO:0055087 IBA
    Ski complex GO:0055087 ISO
 Experiment description of studies that identified Skiv2l in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Skiv2l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Skiv2l is involved
No pathways found





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