Gene description for Col6a1
Gene name collagen, type VI, alpha 1
Gene symbol Col6a1
Other names/aliases RGD1565398
Species Rattus norvegicus
 Database cross references - Col6a1
ExoCarta ExoCarta_294337
Entrez Gene 294337
 Col6a1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Col6a1
Molecular Function
    platelet-derived growth factor binding GO:0048407 ISO
    molecular_function GO:0003674 ND
Biological Process
    endodermal cell differentiation GO:0035987 ISO
    osteoblast differentiation GO:0001649 ISO
    biological_process GO:0008150 ND
    cellular response to amino acid stimulus GO:0071230 ISO
    protein heterotrimerization GO:0070208 ISO
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    cellular_component GO:0005575 ND
    extracellular exosome GO:0070062 ISO
    proteinaceous extracellular matrix GO:0005578 ISO
    extracellular region GO:0005576 TAS
    protein complex GO:0043234 ISO
    membrane GO:0016020 ISO
    sarcolemma GO:0042383 ISO
    extracellular matrix GO:0031012 ISO
 Experiment description of studies that identified Col6a1 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Col6a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Col6a1 is involved
No pathways found





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