Gene description for Kpna5
Gene name karyopherin alpha 5 (importin alpha 6)
Gene symbol Kpna5
Other names/aliases Ipoa6
Species Rattus norvegicus
 Database cross references - Kpna5
ExoCarta ExoCarta_294392
Entrez Gene 294392
UniProt Q56R16  
 Kpna5 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Kpna5
Molecular Function
    protein transporter activity GO:0008565 IEA
Biological Process
    protein import into nucleus GO:0006606 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Kpna5 in exosomes
1
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Kpna5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Kpna5 is involved
No pathways found





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