Gene description for Serinc1
Gene name serine incorporator 1
Gene symbol Serinc1
Other names/aliases LRRGT00191
Tde1l
Tde2
Species Rattus norvegicus
 Database cross references - Serinc1
ExoCarta ExoCarta_294421
Entrez Gene 294421
UniProt Q7TNK0  
 Serinc1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Serinc1
Molecular Function
    L-serine transmembrane transporter activity GO:0015194 IDA
Biological Process
    sphingolipid metabolic process GO:0006665 IDA
    L-serine transport GO:0015825 IDA
    phosphatidylserine metabolic process GO:0006658 IDA
    phospholipid biosynthetic process GO:0008654 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    endoplasmic reticulum membrane GO:0005789 IDA
    integral component of membrane GO:0016021 IBA
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Serinc1 in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Serinc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Serinc1 is involved
No pathways found





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