Gene description for Pelo
Gene name pelota homolog (Drosophila)
Gene symbol Pelo
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Pelo
ExoCarta ExoCarta_294754
Entrez Gene 294754
UniProt Q5XIP1  
 Pelo identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Pelo
Molecular Function
    endonuclease activity GO:0004519 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    cell proliferation GO:0008283 ISO
    cell division GO:0051301 IEA
    nuclear-transcribed mRNA catabolic process, non-stop decay GO:0070481 IEA
    chromosome organization GO:0051276 ISO
    RNA surveillance GO:0071025 IEA
    nucleic acid phosphodiester bond hydrolysis GO:0090305 IEA
    nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Pelo in exosomes
1
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Pelo
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pelo is involved
No pathways found





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