Gene description for Slc1a3
Gene name	solute carrier family 1 (glial high affinity glutamate transporter), member 3
Gene symbol	Slc1a3
Other names/aliases	EAAT1 GLAST GLAST-1 GluT-1
Species	Rattus norvegicus
Database cross references - Slc1a3
ExoCarta	ExoCarta_29483
Vesiclepedia	VP_29483
Entrez Gene	29483
UniProt	P24942
Slc1a3 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Cortical neurones	16446100

Gene ontology annotations for Slc1a3

Molecular Function     L-glutamate transmembrane transporter activity GO:0005313 IBA     L-glutamate transmembrane transporter activity GO:0005313 IDA     L-glutamate transmembrane transporter activity GO:0005313 ISO     L-glutamate transmembrane transporter activity GO:0005313 TAS     high-affinity L-glutamate transmembrane transporter activity GO:0005314 IEA     high-affinity L-glutamate transmembrane transporter activity GO:0005314 IMP     high-affinity L-glutamate transmembrane transporter activity GO:0005314 ISO     high-affinity L-glutamate transmembrane transporter activity GO:0005314 ISS     acidic amino acid transmembrane transporter activity GO:0015172 IEA     acidic amino acid transmembrane transporter activity GO:0015172 ISO     neutral L-amino acid transmembrane transporter activity GO:0015175 IBA     L-amino acid transmembrane transporter activity GO:0015179 IEA     symporter activity GO:0015293 IEA     glutamate:sodium symporter activity GO:0015501 IBA     glutamate:sodium symporter activity GO:0015501 IMP     glutamate:sodium symporter activity GO:0015501 ISO     glutamate:sodium symporter activity GO:0015501 ISS     glutamate binding GO:0016595 IEA     glutamate binding GO:0016595 ISO     amino acid binding GO:0016597 ISO     metal ion binding GO:0046872 IEA Biological Process     dicarboxylic acid transport GO:0006835 IEA     neurotransmitter transport GO:0006836 TAS     intracellular sodium ion homeostasis GO:0006883 IEA     intracellular sodium ion homeostasis GO:0006883 ISO     sensory perception of sound GO:0007605 IEA     sensory perception of sound GO:0007605 ISO     response to xenobiotic stimulus GO:0009410 IEA     response to xenobiotic stimulus GO:0009410 ISO     response to light stimulus GO:0009416 IEA     response to light stimulus GO:0009416 ISO     gamma-aminobutyric acid biosynthetic process GO:0009449 IEA     gamma-aminobutyric acid biosynthetic process GO:0009449 ISO     response to wounding GO:0009611 IEA     response to wounding GO:0009611 ISO     acidic amino acid transport GO:0015800 IEA     neutral amino acid transport GO:0015804 IEA     L-glutamate transmembrane transport GO:0015813 IDA     L-glutamate transmembrane transport GO:0015813 IDA     L-glutamate transmembrane transport GO:0015813 IMP     L-glutamate transmembrane transport GO:0015813 ISO     L-glutamate transmembrane transport GO:0015813 ISO     cranial nerve development GO:0021545 IEA     cranial nerve development GO:0021545 ISO     auditory behavior GO:0031223 IEA     auditory behavior GO:0031223 ISO     malate-aspartate shuttle GO:0043490 IDA     response to antibiotic GO:0046677 IEA     response to antibiotic GO:0046677 ISO     cell morphogenesis involved in neuron differentiation GO:0048667 IEA     cell morphogenesis involved in neuron differentiation GO:0048667 ISO     positive regulation of synaptic transmission GO:0050806 IEA     positive regulation of synaptic transmission GO:0050806 ISO     neuromuscular process controlling balance GO:0050885 IEA     neuromuscular process controlling balance GO:0050885 ISO     L-glutamate import GO:0051938 ISO     L-glutamate import GO:0051938 ISO     D-aspartate import across plasma membrane GO:0070779 IBA     D-aspartate import across plasma membrane GO:0070779 IEA     D-aspartate import across plasma membrane GO:0070779 ISO     D-aspartate import across plasma membrane GO:0070779 ISS     cellular response to cocaine GO:0071314 IEA     cellular response to cocaine GO:0071314 ISO     potassium ion transmembrane transport GO:0071805 IEA     potassium ion transmembrane transport GO:0071805 ISO     potassium ion transmembrane transport GO:0071805 ISS     L-glutamate import across plasma membrane GO:0098712 IBA     L-glutamate import across plasma membrane GO:0098712 IEA     L-glutamate import across plasma membrane GO:0098712 IMP     L-glutamate import across plasma membrane GO:0098712 ISO     L-glutamate import across plasma membrane GO:0098712 ISO     L-glutamate import across plasma membrane GO:0098712 ISS     L-aspartate import across plasma membrane GO:0140009 IBA     L-aspartate import across plasma membrane GO:0140009 IEA     L-aspartate import across plasma membrane GO:0140009 IMP     L-aspartate import across plasma membrane GO:0140009 ISO     L-aspartate import across plasma membrane GO:0140009 ISS     L-alpha-amino acid transmembrane transport GO:1902475 IEA     chloride transmembrane transport GO:1902476 IEA     chloride transmembrane transport GO:1902476 ISO     chloride transmembrane transport GO:1902476 ISS Subcellular Localization     mitochondrial inner membrane GO:0005743 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 IMP     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISS     basal plasma membrane GO:0009925 IDA     cell surface GO:0009986 IEA     cell surface GO:0009986 ISO     basolateral plasma membrane GO:0016323 IDA     cell projection GO:0042995 ISO     neuron projection GO:0043005 IDA     neuron projection GO:0043005 IEA     neuron projection GO:0043005 ISO     neuronal cell body GO:0043025 IDA     neuronal cell body GO:0043025 IEA     neuronal cell body GO:0043025 ISO     dendritic spine GO:0043197 IDA     synapse GO:0045202 IEA     synapse GO:0045202 ISO     cell periphery GO:0071944 ISO     membrane protein complex GO:0098796 IDA