Gene description for Gnb4
Gene name guanine nucleotide binding protein (G protein), beta polypeptide 4
Gene symbol Gnb4
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gnb4
ExoCarta ExoCarta_294962
Entrez Gene 294962
UniProt O35353  
 Gnb4 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Gnb4
Molecular Function
    protein complex binding GO:0032403 ISO
    signal transducer activity GO:0004871 IEA
Biological Process
    signal transduction GO:0007165 IEA
    substantia nigra development GO:0021762 ISO
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    extracellular exosome GO:0070062 ISO
    cell body GO:0044297 IDA
    myelin sheath GO:0043209 ISO
 Experiment description of studies that identified Gnb4 in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Gnb4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gnb4 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here