Gene description for Gmps
Gene name guanine monphosphate synthase
Gene symbol Gmps
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gmps
ExoCarta ExoCarta_295088
Vesiclepedia VP_295088
Entrez Gene 295088
UniProt Q4V7C6  
 Gmps identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gmps
Molecular Function
    GMP synthase activity GO:0003921 IBA
    GMP synthase activity GO:0003921 IDA
    GMP synthase activity GO:0003921 IEA
    GMP synthase activity GO:0003921 ISO
    GMP synthase (glutamine-hydrolyzing) activity GO:0003922 IDA
    GMP synthase (glutamine-hydrolyzing) activity GO:0003922 ISO
    ATP binding GO:0005524 IEA
    enzyme binding GO:0019899 IDA
Biological Process
    GMP biosynthetic process GO:0006177 IBA
    GMP biosynthetic process GO:0006177 IDA
    GMP biosynthetic process GO:0006177 IEA
    GMP biosynthetic process GO:0006177 ISO
    GMP biosynthetic process GO:0006177 ISO
    glutamine metabolic process GO:0006541 IEA
    response to xenobiotic stimulus GO:0009410 IEP
    GMP salvage GO:0032263 IDA
    response to L-cysteine GO:1901367 IDA
Subcellular Localization
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Gmps in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gmps
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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