Gene description for Gmps
Gene name guanine monphosphate synthase
Gene symbol Gmps
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gmps
ExoCarta ExoCarta_295088
Entrez Gene 295088
UniProt Q4V7C6  
 Gmps identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gmps
Molecular Function
    GMP synthase activity GO:0003921 IDA
    GMP synthase (glutamine-hydrolyzing) activity GO:0003922 IEA
    enzyme binding GO:0019899 IDA
    pyrophosphatase activity GO:0016462 IEA
    ATP binding GO:0005524 IEA
Biological Process
    response to drug GO:0042493 IEP
    GMP biosynthetic process GO:0006177 IEA
    glutamine metabolic process GO:0006541 IEP
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Gmps in exosomes
1
Experiment ID 98
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gmps
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gmps is involved
PathwayEvidenceSource
Purine ribonucleoside monophosphate biosynthesis IEA Reactome





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