Gene description for Esyt1
Gene name extended synaptotagmin-like protein 1
Gene symbol Esyt1
Other names/aliases Fam62a
Mbc2
Species Rattus norvegicus
 Database cross references - Esyt1
ExoCarta ExoCarta_29579
Vesiclepedia VP_29579
Entrez Gene 29579
UniProt Q9Z1X1  
 Esyt1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Esyt1
Molecular Function
    calcium ion binding GO:0005509 IBA
    calcium-dependent phospholipid binding GO:0005544 IBA
    lipid binding GO:0008289 IEA
    phosphatidylethanolamine binding GO:0008429 IBA
    phosphatidylcholine binding GO:0031210 IBA
    phosphatidylinositol binding GO:0035091 IBA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    phospholipid transfer activity GO:0120014 IEA
    phospholipid transfer activity GO:0120014 ISO
    phospholipid transfer activity GO:0120014 ISS
Biological Process
    phospholipid transport GO:0015914 IEA
    endoplasmic reticulum-plasma membrane tethering GO:0061817 IEA
    intermembrane lipid transfer GO:0120009 IEA
    intermembrane lipid transfer GO:0120009 ISO
    intermembrane lipid transfer GO:0120009 ISS
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
    endoplasmic reticulum membrane GO:0005789 ISO
    endoplasmic reticulum membrane GO:0005789 ISS
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Esyt1 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Esyt1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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