Gene description for Psme2
Gene name proteasome (prosome, macropain) activator subunit 2
Gene symbol Psme2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Psme2
ExoCarta ExoCarta_29614
Entrez Gene 29614
UniProt Q63798  
 Psme2 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Psme2
Molecular Function
    endopeptidase activator activity GO:0061133 ISO
Biological Process
    antigen processing and presentation of exogenous antigen GO:0019884 ISO
    positive regulation of endopeptidase activity GO:0010950 ISO
Subcellular Localization
    proteasome activator complex GO:0008537 IEA
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Psme2 in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Psme2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psme2 is involved
No pathways found





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