Gene description for Psme2
Gene name proteasome (prosome, macropain) activator subunit 2
Gene symbol Psme2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Psme2
ExoCarta ExoCarta_29614
Vesiclepedia VP_29614
Entrez Gene 29614
UniProt Q63798  
 Psme2 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Psme2
Molecular Function
    identical protein binding GO:0042802 ISO
    endopeptidase activator activity GO:0061133 IBA
    endopeptidase activator activity GO:0061133 ISO
Biological Process
    antigen processing and presentation of exogenous antigen GO:0019884 ISO
    regulation of proteasomal protein catabolic process GO:0061136 IBA
    regulation of G1/S transition of mitotic cell cycle GO:2000045 IBA
Subcellular Localization
    nucleoplasm GO:0005654 IBA
    cytoplasm GO:0005737 IBA
    proteasome activator complex GO:0008537 IEA
 Experiment description of studies that identified Psme2 in sEVs
1
Experiment ID 95
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Psme2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psme2 is involved
PathwayEvidenceSource
Metabolism of proteins IEA Reactome
Post-translational protein modification IEA Reactome
Proteasome assembly IEA Reactome





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