Gene description for Acss1
Gene name acyl-CoA synthetase short-chain family member 1
Gene symbol Acss1
Other names/aliases Acas2l
Species Rattus norvegicus
 Database cross references - Acss1
ExoCarta ExoCarta_296259
Vesiclepedia VP_296259
Entrez Gene 296259
 Acss1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Acss1
Molecular Function
    acetate-CoA ligase activity GO:0003987 IBA
    acetate-CoA ligase activity GO:0003987 IDA
    acetate-CoA ligase activity GO:0003987 ISO
    ATP binding GO:0005524 IEA
    AMP binding GO:0016208 IEA
    propionate-CoA ligase activity GO:0050218 ISO
Biological Process
    acetyl-CoA biosynthetic process GO:0006085 IBA
    acetyl-CoA biosynthetic process GO:0006085 ISO
    acetyl-CoA biosynthetic process GO:0006085 ISO
    acetate biosynthetic process GO:0019413 IDA
    acetyl-CoA biosynthetic process from acetate GO:0019427 IEA
    propionate biosynthetic process GO:0019542 IDA
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    mitochondrial matrix GO:0005759 ISO
 Experiment description of studies that identified Acss1 in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Acss1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acss1 is involved
No pathways found





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