Gene description for Ube2v1
Gene name ubiquitin-conjugating enzyme E2 variant 1
Gene symbol Ube2v1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ube2v1
ExoCarta ExoCarta_296390
Vesiclepedia VP_296390
Entrez Gene 296390
 Ube2v1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Ube2v1
Molecular Function
    ubiquitin conjugating enzyme binding GO:0031624 ISO
    ubiquitin conjugating enzyme activity GO:0061631 ISO
Biological Process
    postreplication repair GO:0006301 IBA
    biological_process GO:0008150 ND
    error-free postreplication DNA repair GO:0042275 ISO
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISO
    positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO
    protein K63-linked ubiquitination GO:0070534 IBA
    protein K63-linked ubiquitination GO:0070534 ISO
    regulation protein catabolic process at postsynapse GO:0140252 IDA
    regulation protein catabolic process at postsynapse GO:0140252 IEP
    regulation protein catabolic process at postsynapse GO:0140252 IMP
    positive regulation of protein K63-linked ubiquitination GO:1902523 ISO
    positive regulation of intracellular signal transduction GO:1902533 ISO
Subcellular Localization
    ubiquitin ligase complex GO:0000151 ISO
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    postsynaptic density GO:0014069 IDA
    membrane GO:0016020 IEA
    ubiquitin conjugating enzyme complex GO:0031371 IBA
    ubiquitin conjugating enzyme complex GO:0031371 ISO
    UBC13-MMS2 complex GO:0031372 ISO
    protein-containing complex GO:0032991 ISO
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
 Experiment description of studies that identified Ube2v1 in sEVs
1
Experiment ID 96
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
3
Experiment ID 98
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Ube2v1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ube2v1 is involved
No pathways found





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