Gene description for Ube2v1
Gene name ubiquitin-conjugating enzyme E2 variant 1
Gene symbol Ube2v1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ube2v1
ExoCarta ExoCarta_296390
Entrez Gene 296390
 Ube2v1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Ube2v1
Molecular Function
    molecular_function GO:0003674 ND
    ubiquitin conjugating enzyme binding GO:0031624 ISO
    ubiquitin protein ligase activity GO:0061630 IBA
    ubiquitin protein ligase binding GO:0031625 IBA
    ubiquitin conjugating enzyme activity GO:0061631 ISO
Biological Process
    protein K63-linked ubiquitination GO:0070534 ISO
    positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO
    error-free postreplication DNA repair GO:0042275 ISO
    biological_process GO:0008150 ND
    postreplication repair GO:0006301 IBA
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO
Subcellular Localization
    protein complex GO:0043234 ISO
    ubiquitin ligase complex GO:0000151 ISO
    ubiquitin conjugating enzyme complex GO:0031371 ISO
    cytoplasm GO:0005737 ISO
    UBC13-UEV1A complex GO:0035370 ISO
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 IBA
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Ube2v1 in exosomes
1
Experiment ID 96
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
3
Experiment ID 98
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Ube2v1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ube2v1 is involved
No pathways found





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