Gene description for Capg
Gene name capping protein (actin filament), gelsolin-like
Gene symbol Capg
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Capg
ExoCarta ExoCarta_297339
Vesiclepedia VP_297339
Entrez Gene 297339
UniProt Q6AYC4  
 Capg identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Capg
Molecular Function
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IBA
    protein domain specific binding GO:0019904 IEA
    protein domain specific binding GO:0019904 ISO
    protein-containing complex binding GO:0044877 ISO
    actin filament binding GO:0051015 IBA
    actin filament binding GO:0051015 IEA
Biological Process
    central nervous system development GO:0007417 IBA
    actin polymerization or depolymerization GO:0008154 IBA
    extracellular matrix disassembly GO:0022617 ISO
    cell projection assembly GO:0030031 IBA
    cell projection assembly GO:0030031 ISO
    actin filament severing GO:0051014 IBA
    barbed-end actin filament capping GO:0051016 IBA
    cellular response to type II interferon GO:0071346 ISO
    positive regulation of podosome assembly GO:0071803 ISO
Subcellular Localization
    ruffle GO:0001726 IEA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 IEA
    nucleolus GO:0005730 ISO
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    centriole GO:0005814 IEA
    centriole GO:0005814 ISO
    actin cytoskeleton GO:0015629 IBA
    lamellipodium GO:0030027 IEA
    melanosome GO:0042470 IEA
    phagocytic vesicle GO:0045335 ISO
    mitotic spindle GO:0072686 IEA
    mitotic spindle GO:0072686 ISO
    Flemming body GO:0090543 IEA
    Flemming body GO:0090543 ISO
 Experiment description of studies that identified Capg in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Capg
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Capg is involved
No pathways found





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