Gene description for Strap
Gene name serine/threonine kinase receptor associated protein
Gene symbol Strap
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Strap
ExoCarta ExoCarta_297699
Vesiclepedia VP_297699
Entrez Gene 297699
UniProt Q5XIG8  
 Strap identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Strap
Molecular Function
    RNA binding GO:0003723 IBA
    mRNA binding GO:0003729 ISO
    signaling receptor binding GO:0005102 ISO
    U2 snRNP binding GO:1990447 ISO
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 ISO
    alternative mRNA splicing, via spliceosome GO:0000380 ISO
    spliceosomal snRNP assembly GO:0000387 IBA
    spliceosomal snRNP assembly GO:0000387 ISO
    spliceosomal snRNP assembly GO:0000387 ISS
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    protein-RNA complex assembly GO:0022618 ISO
    neuron differentiation GO:0030182 ISO
    maintenance of gastrointestinal epithelium GO:0030277 ISO
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
    SMN complex GO:0032797 IBA
    SMN complex GO:0032797 ISO
    SMN complex GO:0032797 ISS
    SMN-Sm protein complex GO:0034719 ISO
    SMN-Sm protein complex GO:0034719 ISS
 Experiment description of studies that identified Strap in sEVs
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Strap
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mib1  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml



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