Gene description for Magoh
Gene name mago-nashi homolog, proliferation-associated (Drosophila)
Gene symbol Magoh
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Magoh
ExoCarta ExoCarta_298385
Entrez Gene 298385
UniProt Q27W02  
 Magoh identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Magoh
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    mRNA transport GO:0051028 IEA
    RNA splicing GO:0008380 IBA
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 ISS
    mRNA processing GO:0006397 IEA
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 ISO
    regulation of translation GO:0006417 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    catalytic step 2 spliceosome GO:0071013 ISO
    exon-exon junction complex GO:0035145 ISO
    nucleus GO:0005634 ISO
    nuclear speck GO:0016607 IEA
 Experiment description of studies that identified Magoh in exosomes
1
Experiment ID 98
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Magoh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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