Gene description for Prps1l1
Gene name phosphoribosyl pyrophosphate synthetase 1-like 1
Gene symbol Prps1l1
Other names/aliases Prps3
Species Rattus norvegicus
 Database cross references - Prps1l1
ExoCarta ExoCarta_298954
Vesiclepedia VP_298954
Entrez Gene 298954
 Prps1l1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Prps1l1
Molecular Function
    magnesium ion binding GO:0000287 IEA
    ribose phosphate diphosphokinase activity GO:0004749 IBA
    ATP binding GO:0005524 IEA
    kinase activity GO:0016301 IEA
Biological Process
    5-phosphoribose 1-diphosphate biosynthetic process GO:0006015 IBA
    5-phosphoribose 1-diphosphate biosynthetic process GO:0006015 IEA
    purine nucleotide biosynthetic process GO:0006164 IBA
    male gonad development GO:0008584 IEP
    ribonucleoside monophosphate biosynthetic process GO:0009156 IEA
Subcellular Localization
    ribose phosphate diphosphokinase complex GO:0002189 IBA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified Prps1l1 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Prps1l1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Prps1l1 is involved
No pathways found





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