Gene description for Gtpbp1
Gene name GTP binding protein 1
Gene symbol Gtpbp1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gtpbp1
ExoCarta ExoCarta_300077
Vesiclepedia VP_300077
Entrez Gene 300077
UniProt D2XV59  
 Gtpbp1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Gtpbp1
Molecular Function
    tRNA binding GO:0000049 ISO
    translation elongation factor activity GO:0003746 IBA
    translation elongation factor activity GO:0003746 ISO
    GTPase activity GO:0003924 IDA
    GTPase activity GO:0003924 IEA
    GTPase activity GO:0003924 ISO
    GTP binding GO:0005525 IEA
    alpha-aminoacyl-tRNA binding GO:1904678 ISO
Biological Process
    cytoplasmic translation GO:0002181 ISO
    translational elongation GO:0006414 IBA
    GTP metabolic process GO:0046039 IDA
    positive regulation of mRNA catabolic process GO:0061014 IDA
Subcellular Localization
    cytoplasmic exosome (RNase complex) GO:0000177 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Gtpbp1 in sEVs
1
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gtpbp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gtpbp1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here