Gene description for SLC40A1
Gene name	solute carrier family 40 (iron-regulated transporter), member 1
Gene symbol	SLC40A1
Other names/aliases	FPN1 HFE4 IREG1 MST079 MSTP079 MTP1 SLC11A3
Species	Homo sapiens
Database cross references - SLC40A1
ExoCarta	ExoCarta_30061
Vesiclepedia	VP_30061
Entrez Gene	30061
HGNC	10909
MIM	604653
UniProt	Q9NP59
SLC40A1 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for SLC40A1

Molecular Function     iron ion transmembrane transporter activity GO:0005381 IBA     iron ion transmembrane transporter activity GO:0005381 IMP     iron ion transmembrane transporter activity GO:0005381 ISS     protein binding GO:0005515 IPI     ferrous iron transmembrane transporter activity GO:0015093 IDA     ferrous iron transmembrane transporter activity GO:0015093 ISS     peptide hormone binding GO:0017046 IBA     peptide hormone binding GO:0017046 IDA     peptide hormone binding GO:0017046 IPI     identical protein binding GO:0042802 IEA     metal ion binding GO:0046872 IEA Biological Process     lymphocyte homeostasis GO:0002260 IEA     endothelium development GO:0003158 IEA     transcription by RNA polymerase II GO:0006366 IEA     intracellular iron ion homeostasis GO:0006879 IMP     apoptotic process GO:0006915 IEA     iron ion transmembrane transport GO:0034755 IBA     iron ion transmembrane transport GO:0034755 IMP     negative regulation of apoptotic process GO:0043066 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     establishment of localization in cell GO:0051649 IEA     spleen trabecula formation GO:0060345 IEA     multicellular organismal-level iron ion homeostasis GO:0060586 ISS     iron ion export across plasma membrane GO:1903988 ISS Subcellular Localization     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 TAS     cytosol GO:0005829 IDA     plasma membrane GO:0005886 IC     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     synaptic vesicle GO:0008021 IEA     membrane GO:0016020 TAS     basolateral plasma membrane GO:0016323 IBA     basolateral plasma membrane GO:0016323 IDA     basolateral plasma membrane GO:0016323 IDA     basolateral plasma membrane GO:0016323 ISS