Gene description for Atp5l
Gene name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
Gene symbol Atp5l
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Atp5l
ExoCarta ExoCarta_300677
Entrez Gene 300677
UniProt Q6PDU7  
 Atp5l identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Atp5l
Molecular Function
    hydrogen ion transmembrane transporter activity GO:0015078 IEA
    ATPase activity GO:0016887 ISO
Biological Process
    ATP metabolic process GO:0046034 IDA
    ATP synthesis coupled proton transport GO:0015986 IEA
Subcellular Localization
    mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 IDA
    mitochondrion GO:0005739 ISO
    mitochondrial proton-transporting ATP synthase complex GO:0005753 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Atp5l in exosomes
1
Experiment ID 94
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Atp5l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Atp5l is involved
PathwayEvidenceSource
Formation of ATP by chemiosmotic coupling IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here