Gene description for Dapk2
Gene name death-associated protein kinase 2
Gene symbol Dapk2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Dapk2
ExoCarta ExoCarta_300799
Entrez Gene 300799
 Dapk2 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Dapk2
Molecular Function
    ATP binding GO:0005524 ISO
    identical protein binding GO:0042802 ISO
    calmodulin-dependent protein kinase activity GO:0004683 IBA
    calmodulin binding GO:0005516 ISO
Biological Process
    intracellular signal transduction GO:0035556 ISO
    protein phosphorylation GO:0006468 ISO
    regulation of apoptotic process GO:0042981 IBA
    regulation of intrinsic apoptotic signaling pathway GO:2001242 ISO
    anoikis GO:0043276 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Dapk2 in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Dapk2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dapk2 is involved
No pathways found





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