Gene description for Gsta4
Gene name glutathione S-transferase alpha 4
Gene symbol Gsta4
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gsta4
ExoCarta ExoCarta_300850
Entrez Gene 300850
UniProt P14942  
 Gsta4 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gsta4
Molecular Function
    drug binding GO:0008144 IDA
    glutathione binding GO:0043295 IDA
    glutathione transferase activity GO:0004364 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    response to nicotine GO:0035094 IEP
    xenobiotic metabolic process GO:0006805 ISO
    response to herbicide GO:0009635 IEP
    cellular response to lithium ion GO:0071285 IEP
    glutathione metabolic process GO:0006749 ISO
    response to zinc ion GO:0010043 IEP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified Gsta4 in exosomes
1
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gsta4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gsta4 is involved
No pathways found





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