Gene description for Ugt1a8
Gene name UDP glycosyltransferase 1 family, polypeptide A8
Gene symbol Ugt1a8
Other names/aliases UDPGT 1-8
Ugt1
Ugt1a9
Species Rattus norvegicus
 Database cross references - Ugt1a8
ExoCarta ExoCarta_301595
Vesiclepedia VP_301595
Entrez Gene 301595
 Ugt1a8 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Ugt1a8
Molecular Function
    UDP-glycosyltransferase activity GO:0008194 IEA
    glucuronosyltransferase activity GO:0015020 IDA
    glucuronosyltransferase activity GO:0015020 TAS
    enzyme binding GO:0019899 IBA
Biological Process
    liver development GO:0001889 IBA
    steroid metabolic process GO:0008202 ISS
    protein glucuronidation GO:0018411 TAS
    coumarin catabolic process GO:0046226 IDA
    cellular glucuronidation GO:0052695 IBA
    cellular response to organic cyclic compound GO:0071407 IEP
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified Ugt1a8 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugt1a8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ugt1a8 is involved
No pathways found





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