Gene description for Mcts1
Gene name malignant T cell amplified sequence 1
Gene symbol Mcts1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Mcts1
ExoCarta ExoCarta_302500
Vesiclepedia VP_302500
Entrez Gene 302500
UniProt Q4G009  
 Mcts1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Mcts1
Molecular Function
    RNA cap binding GO:0000339 IEA
    RNA cap binding GO:0000339 ISO
    RNA cap binding GO:0000339 ISS
    RNA binding GO:0003723 IEA
    ribosomal small subunit binding GO:0043024 IEA
    ribosomal small subunit binding GO:0043024 ISO
    ribosomal small subunit binding GO:0043024 ISS
    translation factor activity, non-nucleic acid binding GO:0045183 IEA
    translation factor activity, non-nucleic acid binding GO:0045183 ISO
    translation factor activity, non-nucleic acid binding GO:0045183 ISS
Biological Process
    formation of translation preinitiation complex GO:0001731 IBA
    formation of translation preinitiation complex GO:0001731 IEA
    formation of translation preinitiation complex GO:0001731 ISO
    translation reinitiation GO:0002188 IEA
    translation reinitiation GO:0002188 ISO
    translation reinitiation GO:0002188 ISS
    regulation of translation GO:0006417 IEA
    DNA damage response GO:0006974 IEA
    ribosome disassembly GO:0032790 IEA
    ribosome disassembly GO:0032790 ISO
    ribosome disassembly GO:0032790 ISS
    IRES-dependent viral translational initiation GO:0075522 IEA
    IRES-dependent viral translational initiation GO:0075522 ISO
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified Mcts1 in sEVs
1
Experiment ID 98
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Mcts1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Snca  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Mcts1 is involved
No pathways found





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