Gene description for Atp6ap2
Gene name	ATPase, H+ transporting, lysosomal accessory protein 2
Gene symbol	Atp6ap2
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Atp6ap2
ExoCarta	ExoCarta_302526
Vesiclepedia	VP_302526
Entrez Gene	302526
UniProt	Q6AXS4
Atp6ap2 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Atp6ap2

Molecular Function     signaling receptor activity GO:0038023 IEA Biological Process     angiotensin maturation GO:0002003 IEA     angiotensin maturation GO:0002003 ISO     lysosomal lumen acidification GO:0007042 IEA     lysosomal lumen acidification GO:0007042 ISO     lysosomal lumen acidification GO:0007042 ISS     biological_process GO:0008150 ND     central nervous system maturation GO:0021626 IEA     central nervous system maturation GO:0021626 ISO     central nervous system maturation GO:0021626 ISS     rostrocaudal neural tube patterning GO:0021903 IEA     rostrocaudal neural tube patterning GO:0021903 ISO     positive regulation of Wnt signaling pathway GO:0030177 IBA     positive regulation of Wnt signaling pathway GO:0030177 ISO     positive regulation of transforming growth factor beta1 production GO:0032914 IEA     positive regulation of transforming growth factor beta1 production GO:0032914 ISO     regulation of MAPK cascade GO:0043408 IEA     regulation of MAPK cascade GO:0043408 ISO     eye pigmentation GO:0048069 IEA     eye pigmentation GO:0048069 ISO     head morphogenesis GO:0060323 IEA     head morphogenesis GO:0060323 ISO     positive regulation of canonical Wnt signaling pathway GO:0090263 IEA     positive regulation of canonical Wnt signaling pathway GO:0090263 ISO     positive regulation of canonical Wnt signaling pathway GO:0090263 ISS     synaptic vesicle lumen acidification GO:0097401 IEA     synaptic vesicle lumen acidification GO:0097401 ISO Subcellular Localization     vacuolar proton-transporting V-type ATPase, V0 domain GO:0000220 ISS     autophagosome membrane GO:0000421 IEA     extracellular space GO:0005615 IDA     lysosome GO:0005764 ISO     lysosomal membrane GO:0005765 IEA     lysosomal membrane GO:0005765 ISO     lysosomal membrane GO:0005765 ISS     endoplasmic reticulum membrane GO:0005789 IEA     endoplasmic reticulum membrane GO:0005789 ISO     external side of plasma membrane GO:0009897 IBA     external side of plasma membrane GO:0009897 IEA     external side of plasma membrane GO:0009897 ISO     endosome membrane GO:0010008 IEA     endosome membrane GO:0010008 ISO     endosome membrane GO:0010008 ISS     membrane GO:0016020 ISO     apical plasma membrane GO:0016324 IDA     vacuolar proton-transporting V-type ATPase complex GO:0016471 IEA     vacuolar proton-transporting V-type ATPase complex GO:0016471 ISO     vacuolar proton-transporting V-type ATPase complex GO:0016471 ISS     axon GO:0030424 IEA     clathrin-coated vesicle membrane GO:0030665 IEA     synaptic vesicle membrane GO:0030672 EXP     synaptic vesicle membrane GO:0030672 IDA     synaptic vesicle membrane GO:0030672 IEA     dendritic spine membrane GO:0032591 IEA     cell body GO:0044297 IDA     postsynaptic membrane GO:0045211 IEA