Gene description for Fahd1
Gene name fumarylacetoacetate hydrolase domain containing 1
Gene symbol Fahd1
Other names/aliases RGD1304560
Species Rattus norvegicus
 Database cross references - Fahd1
ExoCarta ExoCarta_302980
Entrez Gene 302980
UniProt Q6AYQ8  
 Fahd1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Fahd1
Molecular Function
    acetylpyruvate hydrolase activity GO:0018773 ISS
    metal ion binding GO:0046872 IEA
    acylpyruvate hydrolase activity GO:0047621 IEA
    fumarylpyruvate hydrolase activity GO:0034545 ISS
    oxaloacetate decarboxylase activity GO:0008948 ISS
Biological Process
    metabolic process GO:0008152 IEA
Subcellular Localization
    cytosol GO:0005829 ISS
    mitochondrion GO:0005739 ISS
    mitochondrial inner membrane GO:0005743 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Fahd1 in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Fahd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fahd1 is involved
No pathways found





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