Gene description for HADHB
Gene name hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
Gene symbol HADHB
Other names/aliases ECHB
MSTP029
MTPB
TP-BETA
Species Homo sapiens
 Database cross references - HADHB
ExoCarta ExoCarta_3032
Vesiclepedia VP_3032
Entrez Gene 3032
HGNC 4803
MIM 143450
UniProt P55084  
 HADHB identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for HADHB
Molecular Function
    RNA binding GO:0003723 HDA
    3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 TAS
    acetyl-CoA C-acetyltransferase activity GO:0003985 IBA
    acetyl-CoA C-acyltransferase activity GO:0003988 TAS
    enoyl-CoA hydratase activity GO:0004300 TAS
    protein binding GO:0005515 IPI
    acetyl-CoA C-myristoyltransferase activity GO:0050633 IEA
    lncRNA binding GO:0106222 IEA
Biological Process
    fatty acid beta-oxidation GO:0006635 IBA
    fatty acid beta-oxidation GO:0006635 IDA
    fatty acid beta-oxidation GO:0006635 IEA
    gene expression GO:0010467 IEA
    cellular response to lipopolysaccharide GO:0071222 IEA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 NAS
    mitochondrial envelope GO:0005740 TAS
    mitochondrial outer membrane GO:0005741 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    endoplasmic reticulum GO:0005783 IDA
    mitochondrial fatty acid beta-oxidation multienzyme complex GO:0016507 IBA
    mitochondrial fatty acid beta-oxidation multienzyme complex GO:0016507 IPI
    mitochondrial nucleoid GO:0042645 IDA
 Experiment description of studies that identified HADHB in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for HADHB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Co-fractionation Homo sapiens
2 ITGB1 3688
Co-fractionation Homo sapiens
3 GABARAPL1 23710
Affinity Capture-MS Homo sapiens
4 PDHA1 5160
Co-fractionation Homo sapiens
5 RPA2 6118
Proximity Label-MS Homo sapiens
6 EMC2 9694
Co-fractionation Homo sapiens
7 RALY 22913
Co-fractionation Homo sapiens
8 Edc4  
Affinity Capture-MS Mus musculus
9 SPRTN  
Affinity Capture-MS Homo sapiens
10 VARS 7407
Co-fractionation Homo sapiens
11 UBE2O 63893
Affinity Capture-MS Homo sapiens
12 RAB1A 5861
Co-fractionation Homo sapiens
13 TK1 7083
Two-hybrid Homo sapiens
14 GALNT2 2590
Co-fractionation Homo sapiens
15 NDUFS1 4719
Co-fractionation Homo sapiens
16 PLEKHG6  
Affinity Capture-MS Homo sapiens
17 PTMA 5757
Co-fractionation Homo sapiens
18 SLC39A4 55630
Affinity Capture-MS Homo sapiens
19 SKI 6497
Affinity Capture-MS Homo sapiens
20 CALU 813
Co-fractionation Homo sapiens
21 ARL6IP5 10550
Co-fractionation Homo sapiens
22 CDH5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 TMEFF1  
Affinity Capture-MS Homo sapiens
24 ADRB2  
Affinity Capture-MS Homo sapiens
25 GPC1 2817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 PLOD1 5351
Co-fractionation Homo sapiens
27 ZBTB41  
Cross-Linking-MS (XL-MS) Homo sapiens
28 STON2 85439
Co-fractionation Homo sapiens
29 MAP4 4134
Co-fractionation Homo sapiens
30 APOE 348
Co-fractionation Homo sapiens
31 UBC 7316
Affinity Capture-MS Homo sapiens
32 ARRDC1 92714
Affinity Capture-MS Homo sapiens
33 DNAJC25 548645
Affinity Capture-MS Homo sapiens
34 TROVE2 6738
Co-fractionation Homo sapiens
35 NDUFA4 4697
Co-fractionation Homo sapiens
36 BMPR1A 657
Cross-Linking-MS (XL-MS) Homo sapiens
37 ASPH 444
Co-fractionation Homo sapiens
38 RTN4 57142
Co-fractionation Homo sapiens
39 CPT1A 1374
Co-fractionation Homo sapiens
40 RAB6A 5870
Co-fractionation Homo sapiens
41 ATP5L 10632
Co-fractionation Homo sapiens
42 PTGES2 80142
Co-fractionation Homo sapiens
43 GRB7 2886
Two-hybrid Homo sapiens
44 MAP1LC3B 81631
Affinity Capture-MS Homo sapiens
45 CHCHD4  
Two-hybrid Homo sapiens
46 LAMTOR1 55004
Co-fractionation Homo sapiens
47 NDUFB9 4715
Co-fractionation Homo sapiens
48 PLEKHG4  
Affinity Capture-MS Homo sapiens
49 MGST1 4257
Co-fractionation Homo sapiens
50 DDA1  
Affinity Capture-MS Homo sapiens
51 NDUFS3 4722
Co-fractionation Homo sapiens
52 B3GNT2 10678
Affinity Capture-MS Homo sapiens
53 OGDH 4967
Co-fractionation Homo sapiens
54 PRDX3 10935
Co-fractionation Homo sapiens
55 KIF23 9493
Affinity Capture-MS Homo sapiens
56 MCM2 4171
Affinity Capture-MS Homo sapiens
57 LGALS1 3956
Affinity Capture-MS Homo sapiens
58 COX7A2L 9167
Co-fractionation Homo sapiens
59 IGSF8 93185
Affinity Capture-MS Homo sapiens
60 CYB5R1 51706
Co-fractionation Homo sapiens
61 RAC1 5879
Co-fractionation Homo sapiens
62 NIT1 4817
Affinity Capture-MS Homo sapiens
63 NDUFA5 4698
Co-fractionation Homo sapiens
64 GNB2 2783
Co-fractionation Homo sapiens
65 COA3 28958
Co-fractionation Homo sapiens
66 COX7A2 1347
Co-fractionation Homo sapiens
67 RPS8 6202
Co-fractionation Homo sapiens
68 PPP6R1 22870
Affinity Capture-MS Homo sapiens
69 DDOST 1650
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
70 CXCR4 7852
Affinity Capture-MS Homo sapiens
71 MALSU1  
Affinity Capture-MS Homo sapiens
72 HSP90B1 7184
Co-fractionation Homo sapiens
73 ATP5O 539
Co-fractionation Homo sapiens
74 PGRMC2 10424
Co-fractionation Homo sapiens
75 BMPR1B 658
Cross-Linking-MS (XL-MS) Homo sapiens
76 FANCD2  
Affinity Capture-MS Homo sapiens
77 C20orf24  
Co-fractionation Homo sapiens
78 RCC1 1104
Two-hybrid Homo sapiens
79 LRRC46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 TNNI3K  
Two-hybrid Homo sapiens
81 NDUFV1 4723
Co-fractionation Homo sapiens
82 MME 4311
Co-fractionation Homo sapiens
83 TOMM40 10452
Co-fractionation Homo sapiens
84 ATP6V0D1 9114
Co-fractionation Homo sapiens
85 ZCCHC10  
Affinity Capture-MS Homo sapiens
86 MRPS7 51081
Affinity Capture-MS Homo sapiens
87 CALR 811
Co-fractionation Homo sapiens
88 MECP2 4204
Affinity Capture-MS Homo sapiens
89 COX17  
Two-hybrid Homo sapiens
90 ANKRD34C  
Co-fractionation Homo sapiens
91 ACTB 60
Co-fractionation Homo sapiens
92 UQCRQ 27089
Co-fractionation Homo sapiens
93 ARHGAP9 64333
Affinity Capture-MS Homo sapiens
94 FAM20C 56975
Affinity Capture-MS Homo sapiens
95 NDUFS5 4725
Co-fractionation Homo sapiens
96 SLC25A3 5250
Co-fractionation Homo sapiens
97 NDUFB10 4716
Co-fractionation Homo sapiens
98 KIF14 9928
Affinity Capture-MS Homo sapiens
99 STOML2 30968
Co-fractionation Homo sapiens
100 LRRC59 55379
Co-fractionation Homo sapiens
101 Mgp 17313
Affinity Capture-MS Mus musculus
102 ANXA7 310
Two-hybrid Homo sapiens
103 Cdh1 12550
Affinity Capture-MS Mus musculus
104 ATP5A1 498
Co-fractionation Homo sapiens
105 ATP2A1 487
Affinity Capture-MS Homo sapiens
106 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
107 SET 6418
Affinity Capture-MS Homo sapiens
108 RTF1 23168
Affinity Capture-MS Homo sapiens
109 RFC5 5985
Co-fractionation Homo sapiens
110 C9orf78 51759
Affinity Capture-MS Homo sapiens
111 CDKN1A  
Two-hybrid Homo sapiens
112 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 MAP1B 4131
Co-fractionation Homo sapiens
114 RALA 5898
Co-fractionation Homo sapiens
115 NDUFA8 4702
Co-fractionation Homo sapiens
116 REXO4  
Affinity Capture-MS Homo sapiens
117 RPA4  
Proximity Label-MS Homo sapiens
118 USP36  
Affinity Capture-MS Homo sapiens
119 ATF2  
Affinity Capture-MS Homo sapiens
120 RELL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
122 CFDP1  
Affinity Capture-MS Homo sapiens
123 POTEI 653269
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 IPO9 55705
Affinity Capture-MS Homo sapiens
125 CHMP4B 128866
Affinity Capture-MS Homo sapiens
126 TAL1  
Affinity Capture-MS Homo sapiens
127 CDH8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 DNAJC10 54431
Co-fractionation Homo sapiens
129 ACTN4 81
Co-fractionation Homo sapiens
130 NTRK1 4914
Affinity Capture-MS Homo sapiens
131 KCNA6  
Affinity Capture-MS Homo sapiens
132 OPA1 4976
Co-fractionation Homo sapiens
133 ERP29 10961
Co-fractionation Homo sapiens
134 DNAJA1 3301
Co-fractionation Homo sapiens
135 PTPRD 5789
Affinity Capture-MS Homo sapiens
136 TFAM 7019
Co-fractionation Homo sapiens
137 CYC1 1537
Co-fractionation Homo sapiens
138 KPNB1 3837
Affinity Capture-MS Homo sapiens
139 RPN1 6184
Co-fractionation Homo sapiens
140 USMG5 84833
Co-fractionation Homo sapiens
141 PML 5371
Co-fractionation Homo sapiens
142 GNAI2 2771
Co-fractionation Homo sapiens
143 APOL2 23780
Co-fractionation Homo sapiens
144 Ptcd3  
Two-hybrid Mus musculus
145 RPLP0P6 220717
Co-fractionation Homo sapiens
146 AGPS 8540
Co-fractionation Homo sapiens
147 YAP1 10413
Affinity Capture-MS Homo sapiens
148 SDPR 8436
Co-fractionation Homo sapiens
149 MYL12A 10627
Co-fractionation Homo sapiens
150 VDAC2 7417
Co-fractionation Homo sapiens
151 Ksr1  
Affinity Capture-MS Mus musculus
152 CCR6  
Affinity Capture-MS Homo sapiens
153 ATP5B 506
Co-fractionation Homo sapiens
154 TOMM5  
Co-fractionation Homo sapiens
155 MMGT1 93380
Co-fractionation Homo sapiens
156 COX4I1 1327
Co-fractionation Homo sapiens
157 SSR4 6748
Co-fractionation Homo sapiens
158 ANLN 54443
Affinity Capture-MS Homo sapiens
159 PHB 5245
Co-fractionation Homo sapiens
160 HNRNPD 3184
Co-fractionation Homo sapiens
161 HSPA5 3309
Co-fractionation Homo sapiens
162 PSMA3 5684
Affinity Capture-MS Homo sapiens
163 COX5B 1329
Co-fractionation Homo sapiens
164 TMED9 54732
Co-fractionation Homo sapiens
165 HADHA 3030
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 RPN2 6185
Co-fractionation Homo sapiens
167 LEO1 123169
Affinity Capture-MS Homo sapiens
168 CANX 821
Co-fractionation Homo sapiens
169 SYNDIG1  
Affinity Capture-MS Homo sapiens
170 MTIF2 4528
Proximity Label-MS Homo sapiens
171 ICAM1 3383
Co-fractionation Homo sapiens
172 KIF20A 10112
Affinity Capture-MS Homo sapiens
173 NDUFA9 4704
Co-fractionation Homo sapiens
174 PCCB 5096
Co-fractionation Homo sapiens
175 ECT2 1894
Affinity Capture-MS Homo sapiens
176 ATP2B1 490
Co-fractionation Homo sapiens
177 RPL35 11224
Affinity Capture-MS Homo sapiens
178 UQCRC2 7385
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
179 IQCB1  
Affinity Capture-MS Homo sapiens
180 UBE2L6 9246
Affinity Capture-MS Homo sapiens
181 ASIC2  
Affinity Capture-MS Homo sapiens
182 TUBB1 81027
Co-fractionation Homo sapiens
183 CTCF  
Co-fractionation Homo sapiens
184 HSP90AB1 3326
Co-fractionation Homo sapiens
185 CUL3 8452
Affinity Capture-MS Homo sapiens
186 DES 1674
Co-fractionation Homo sapiens
187 BTF3 689
Affinity Capture-MS Homo sapiens
188 PDIA3 2923
Co-fractionation Homo sapiens
189 EGFR 1956
Affinity Capture-MS Homo sapiens
190 HSD17B10 3028
Two-hybrid Homo sapiens
191 PCYOX1 51449
Co-fractionation Homo sapiens
192 FBXO6 26270
Affinity Capture-MS Homo sapiens
193 SRF  
Affinity Capture-MS Homo sapiens
194 RPL7L1 285855
Affinity Capture-MS Homo sapiens
195 NAF1  
Affinity Capture-MS Homo sapiens
196 RIPK4  
Affinity Capture-MS Homo sapiens
197 SPCS2 9789
Co-fractionation Homo sapiens
198 SDC2 6383
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 MLEC 9761
Co-fractionation Homo sapiens
200 TFCP2 7024
Affinity Capture-MS Homo sapiens
201 SOX15  
Affinity Capture-MS Homo sapiens
202 ZNF782  
Co-fractionation Homo sapiens
203 SLC25A24 29957
Co-fractionation Homo sapiens
204 CDK2 1017
Affinity Capture-MS Homo sapiens
205 SAAL1 113174
Affinity Capture-MS Homo sapiens
206 SEPT2 4735
Co-fractionation Homo sapiens
207 ZMPSTE24 10269
Co-fractionation Homo sapiens
208 IL7R  
Affinity Capture-MS Homo sapiens
209 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 RPA3 6119
Proximity Label-MS Homo sapiens
211 SLC3A2 6520
Co-fractionation Homo sapiens
212 EZR 7430
Co-fractionation Homo sapiens
213 TIMM8B 26521
Two-hybrid Homo sapiens
214 ATP6V1A 523
Co-fractionation Homo sapiens
215 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
216 MOGS 7841
Co-fractionation Homo sapiens
217 UQCRC1 7384
Co-fractionation Homo sapiens
218 ATP1B1 481
Co-fractionation Homo sapiens
219 MYCN  
Affinity Capture-MS Homo sapiens
220 DNAH8 1769
Co-fractionation Homo sapiens
221 DDB1 1642
Affinity Capture-MS Homo sapiens
222 DNAJC1 64215
Affinity Capture-MS Homo sapiens
223 NEK11  
Co-fractionation Homo sapiens
224 DDRGK1 65992
Affinity Capture-MS Homo sapiens
225 Dynll1 56455
Two-hybrid Mus musculus
226 NDUFA3  
Co-fractionation Homo sapiens
227 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
228 GANAB 23193
Co-fractionation Homo sapiens
229 COX2 4513
Co-fractionation Homo sapiens
230 DYM  
Affinity Capture-MS Homo sapiens
231 CEBPA  
Protein-peptide Homo sapiens
232 HSPA9 3313
Co-fractionation Homo sapiens
233 HLA-A 3105
Co-fractionation Homo sapiens
234 Prkar2a 19087
Affinity Capture-MS Mus musculus
235 CORO1C 23603
Co-fractionation Homo sapiens
236 C9orf72  
Affinity Capture-MS Homo sapiens
237 NDUFS2 4720
Co-fractionation Homo sapiens
238 SCCPDH 51097
Co-fractionation Homo sapiens
239 HUWE1 10075
Affinity Capture-MS Homo sapiens
240 EIF3H 8667
Affinity Capture-MS Homo sapiens
241 GBAS 2631
Co-fractionation Homo sapiens
242 RRBP1 6238
Co-fractionation Homo sapiens
243 IMMT 10989
Co-fractionation Homo sapiens
244 TOR1AIP2 163590
Co-fractionation Homo sapiens
245 NES 10763
Affinity Capture-MS Homo sapiens
246 SLC4A1 6521
Co-fractionation Homo sapiens
247 GRK5 2869
Affinity Capture-MS Homo sapiens
248 EDIL3 10085
Co-fractionation Homo sapiens
249 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
250 PHB2 11331
Co-fractionation Homo sapiens
251 TMED10 10972
Co-fractionation Homo sapiens
252 VDAC3 7419
Co-fractionation Homo sapiens
253 HSPB2  
Two-hybrid Homo sapiens
254 SMN1 6606
Two-hybrid Homo sapiens
255 BKRF1  
Affinity Capture-MS
256 DNAJC19 131118
Affinity Capture-MS Homo sapiens
257 NR3C1 2908
Affinity Capture-MS Homo sapiens
258 TP53 7157
Affinity Capture-MS Homo sapiens
259 POTEF 728378
Co-fractionation Homo sapiens
260 CIT 11113
Affinity Capture-MS Homo sapiens
261 TUBG1 7283
Affinity Capture-MS Homo sapiens
262 PEX19 5824
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 SUOX  
Two-hybrid Homo sapiens
264 ZNF746  
Affinity Capture-MS Homo sapiens
265 ABHD10 55347
Affinity Capture-MS Homo sapiens
266 SMARCC1 6599
Cross-Linking-MS (XL-MS) Homo sapiens
267 LRPPRC 10128
Co-fractionation Homo sapiens
268 TPTE  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
269 BCKDHA 593
Co-fractionation Homo sapiens
270 COX5A 9377
Co-fractionation Homo sapiens
271 GABARAPL2 11345
Affinity Capture-MS Homo sapiens
272 NIPSNAP1 8508
Co-fractionation Homo sapiens
273 SQSTM1 8878
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 ATG101  
Affinity Capture-MS Homo sapiens
275 NDUFS7 374291
Co-fractionation Homo sapiens
276 PDHB 5162
Co-fractionation Homo sapiens
277 COX8A  
Co-fractionation Homo sapiens
278 CAPZB 832
Affinity Capture-MS Homo sapiens
279 DDX17 10521
Two-hybrid Homo sapiens
280 GNB1 2782
Co-fractionation Homo sapiens
281 MKI67  
Affinity Capture-MS Homo sapiens
282 KPNA3 3839
Co-fractionation Homo sapiens
283 GNG5 2787
Co-fractionation Homo sapiens
284 SFXN1 94081
Co-fractionation Homo sapiens
285 PPM1G 5496
Co-fractionation Homo sapiens
286 UFL1 23376
Affinity Capture-MS Homo sapiens
287 NF1 4763
Negative Genetic Homo sapiens
288 Arhgap6  
Affinity Capture-MS Mus musculus
289 ATP6V0C 527
Co-fractionation Homo sapiens
290 NDUFS8 4728
Co-fractionation Homo sapiens
291 PLOD3 8985
Co-fractionation Homo sapiens
292 ARHGAP36  
Affinity Capture-MS Homo sapiens
293 CYLD  
Affinity Capture-MS Homo sapiens
294 RAB7A 7879
Co-fractionation Homo sapiens
295 ATP1A1 476
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
296 HEATR3 55027
Affinity Capture-MS Homo sapiens
297 SDC4 6385
Affinity Capture-MS Homo sapiens
298 CYB5R3 1727
Co-fractionation Homo sapiens
299 AP3B2 8120
Co-fractionation Homo sapiens
300 SERBP1 26135
Affinity Capture-MS Homo sapiens
301 Tnpo1 238799
Affinity Capture-MS Mus musculus
302 CUL7 9820
Affinity Capture-MS Homo sapiens
303 ATP5C1 509
Co-fractionation Homo sapiens
304 COX7C 1350
Co-fractionation Homo sapiens
305 CD44 960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 NAP1L1 4673
Co-fractionation Homo sapiens
307 SRP9 6726
Affinity Capture-MS Homo sapiens
308 C17orf80 55028
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 CNR2  
Affinity Capture-MS Homo sapiens
310 YBEY  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 SNRNP200 23020
Co-fractionation Homo sapiens
312 PHF8  
Co-fractionation Homo sapiens
313 PRMT1 3276
Affinity Capture-MS Homo sapiens
314 C11orf58  
Co-fractionation Homo sapiens
315 REPIN1  
Affinity Capture-MS Homo sapiens
316 ESYT1 23344
Co-fractionation Homo sapiens
317 Smn1 20595
Affinity Capture-MS Mus musculus
318 MFGE8 4240
Co-fractionation Homo sapiens
319 MGST3 4259
Co-fractionation Homo sapiens
320 EP300 2033
Affinity Capture-MS Homo sapiens
321 CASC3  
Co-fractionation Homo sapiens
322 MTCH2 23788
Co-fractionation Homo sapiens
323 COX6C 1345
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here