Gene description for G6pc3
Gene name glucose 6 phosphatase, catalytic, 3
Gene symbol G6pc3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - G6pc3
ExoCarta ExoCarta_303565
Vesiclepedia VP_303565
Entrez Gene 303565
UniProt Q6AZ83  
 G6pc3 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for G6pc3
Molecular Function
    glucose-6-phosphatase activity GO:0004346 IBA
    glucose-6-phosphatase activity GO:0004346 IDA
    glucose-6-phosphatase activity GO:0004346 IEA
    glucose-6-phosphatase activity GO:0004346 ISO
Biological Process
    gluconeogenesis GO:0006094 IBA
    gluconeogenesis GO:0006094 IDA
    gluconeogenesis GO:0006094 IEA
    gluconeogenesis GO:0006094 ISO
    glucose-6-phosphate transport GO:0015760 ISO
    glucose 6-phosphate metabolic process GO:0051156 IBA
    glucose 6-phosphate metabolic process GO:0051156 IDA
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 IBA
 Experiment description of studies that identified G6pc3 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for G6pc3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which G6pc3 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glucose metabolism IEA Reactome
Metabolism IEA Reactome
Metabolism of carbohydrates IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here