Gene description for G6pc3
Gene name glucose 6 phosphatase, catalytic, 3
Gene symbol G6pc3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - G6pc3
ExoCarta ExoCarta_303565
Entrez Gene 303565
UniProt Q6AZ83  
 G6pc3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for G6pc3
Molecular Function
    glucose-6-phosphatase activity GO:0004346 ISO
Biological Process
    glucose 6-phosphate metabolic process GO:0051156 IDA
    gluconeogenesis GO:0006094 IEA
    dephosphorylation GO:0016311 ISO
    glucose-6-phosphate transport GO:0015760 ISO
    phosphate-containing compound metabolic process GO:0006796 IDA
Subcellular Localization
    membrane GO:0016020 ISO
    endoplasmic reticulum GO:0005783 ISO
    integral component of endoplasmic reticulum membrane GO:0030176 IBA
 Experiment description of studies that identified G6pc3 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for G6pc3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which G6pc3 is involved
PathwayEvidenceSource
Glucose transport IEA Reactome





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