Gene description for Daglb
Gene name diacylglycerol lipase, beta
Gene symbol Daglb
Other names/aliases RGD1310193
Species Rattus norvegicus
 Database cross references - Daglb
ExoCarta ExoCarta_304289
Vesiclepedia VP_304289
Entrez Gene 304289
 Daglb identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Daglb
Molecular Function
    triacylglycerol lipase activity GO:0004806 IBA
    triacylglycerol lipase activity GO:0004806 IEA
    triacylglycerol lipase activity GO:0004806 ISO
    triacylglycerol lipase activity GO:0004806 ISS
    lipase activity GO:0016298 ISO
    lipase activity GO:0016298 ISS
    metal ion binding GO:0046872 IEA
    monoacylglycerol lipase activity GO:0047372 IEA
    monoacylglycerol lipase activity GO:0047372 ISO
Biological Process
    prostaglandin biosynthetic process GO:0001516 IEA
    prostaglandin biosynthetic process GO:0001516 ISO
    prostaglandin biosynthetic process GO:0001516 ISS
    monoacylglycerol biosynthetic process GO:0006640 IEA
    monoacylglycerol biosynthetic process GO:0006640 ISO
    icosanoid metabolic process GO:0006690 ISO
    icosanoid metabolic process GO:0006690 ISS
    neuroblast proliferation GO:0007405 IEA
    neuroblast proliferation GO:0007405 ISO
    positive regulation of triglyceride catabolic process GO:0010898 IEA
    positive regulation of triglyceride catabolic process GO:0010898 ISO
    positive regulation of triglyceride catabolic process GO:0010898 ISS
    lipid catabolic process GO:0016042 IEA
    arachidonate metabolic process GO:0019369 IBA
    arachidonate metabolic process GO:0019369 IEA
    arachidonate metabolic process GO:0019369 ISO
    arachidonate metabolic process GO:0019369 ISO
    arachidonate metabolic process GO:0019369 ISS
    neurogenesis GO:0022008 IBA
    neurogenesis GO:0022008 ISO
    diacylglycerol catabolic process GO:0046340 IBA
    regulation of inflammatory response GO:0050727 IEA
    regulation of inflammatory response GO:0050727 ISO
    regulation of inflammatory response GO:0050727 ISS
    cannabinoid biosynthetic process GO:1901696 IEA
    cannabinoid biosynthetic process GO:1901696 ISO
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
 Experiment description of studies that identified Daglb in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Daglb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Daglb is involved
No pathways found





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