Gene description for Daglb
Gene name diacylglycerol lipase, beta
Gene symbol Daglb
Other names/aliases RGD1310193
Species Rattus norvegicus
 Database cross references - Daglb
ExoCarta ExoCarta_304289
Entrez Gene 304289
 Daglb identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Daglb
Molecular Function
    metal ion binding GO:0046872 IEA
    lipase activity GO:0016298 IBA
    hydrolase activity GO:0016787 IEA
Biological Process
    neuroblast proliferation GO:0007405 ISO
    lipid catabolic process GO:0016042 IEA
    arachidonic acid metabolic process GO:0019369 ISO
    transport GO:0006810 IEA
    neurotransmitter biosynthetic process GO:0042136 ISO
    neurogenesis GO:0022008 ISO
    lipid metabolic process GO:0006629 IBA
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    bounding membrane of organelle GO:0098588 IBA
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Daglb in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Daglb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Daglb is involved
No pathways found





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