Gene description for Tmem184a
Gene name transmembrane protein 184A
Gene symbol Tmem184a
Other names/aliases RGD1306702
Species Rattus norvegicus
 Database cross references - Tmem184a
ExoCarta ExoCarta_304325
Vesiclepedia VP_304325
Entrez Gene 304325
UniProt Q4QQS1  
 Tmem184a identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Tmem184a
Molecular Function
    heparin binding GO:0008201 ISS
    transmembrane transporter activity GO:0022857 IBA
Biological Process
    germ-line sex determination GO:0018992 ISO
    regulation of protein localization GO:0032880 ISO
    regulation of secretion GO:0051046 ISO
    transmembrane transport GO:0055085 IEA
Subcellular Localization
    endosome GO:0005768 ISO
    endosome GO:0005768 ISS
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 IEA
    transport vesicle membrane GO:0030658 IEA
    cytoplasmic vesicle membrane GO:0030659 ISS
    secretory granule membrane GO:0030667 ISO
    secretory granule membrane GO:0030667 ISS
    early endosome membrane GO:0031901 IBA
    early endosome membrane GO:0031901 ISO
    early endosome membrane GO:0031901 ISS
    perinuclear region of cytoplasm GO:0048471 ISS
 Experiment description of studies that identified Tmem184a in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Tmem184a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmem184a is involved
No pathways found





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