Gene description for Serpinb13
Gene name serpin peptidase inhibitor, clade B (ovalbumin), member 13
Gene symbol Serpinb13
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Serpinb13
ExoCarta ExoCarta_304690
Vesiclepedia VP_304690
Entrez Gene 304690
 Serpinb13 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Serpinb13
Molecular Function
    protease binding GO:0002020 ISO
    serine-type endopeptidase inhibitor activity GO:0004867 ISO
    cysteine-type endopeptidase inhibitor activity GO:0004869 ISO
Biological Process
    negative regulation of endopeptidase activity GO:0010951 ISO
    negative regulation of keratinocyte apoptotic process GO:1902173 ISO
Subcellular Localization
    extracellular space GO:0005615 IBA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    nuclear speck GO:0016607 IEA
    nuclear speck GO:0016607 ISO
 Experiment description of studies that identified Serpinb13 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Serpinb13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mib1  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Serpinb13 is involved
No pathways found





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