Gene description for Serpinb13
Gene name serpin peptidase inhibitor, clade B (ovalbumin), member 13
Gene symbol Serpinb13
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Serpinb13
ExoCarta ExoCarta_304690
Entrez Gene 304690
 Serpinb13 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Serpinb13
Molecular Function
    protease binding GO:0002020 ISO
    cysteine-type endopeptidase inhibitor activity GO:0004869 ISO
    serine-type endopeptidase inhibitor activity GO:0004867 ISO
Biological Process
    negative regulation of keratinocyte apoptotic process GO:1902173 ISO
    negative regulation of endopeptidase activity GO:0010951 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    nucleoplasm GO:0005654 ISO
    extracellular space GO:0005615 IBA
    nucleolus GO:0005730 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Serpinb13 in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Serpinb13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Serpinb13 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here