Gene description for Letm1
Gene name leucine zipper-EF-hand containing transmembrane protein 1
Gene symbol Letm1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Letm1
ExoCarta ExoCarta_305457
Entrez Gene 305457
UniProt Q5XIN6  
 Letm1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Letm1
Molecular Function
    metal ion binding GO:0046872 IEA
Biological Process
    cristae formation GO:0042407 ISO
Subcellular Localization
    mitochondrial inner membrane GO:0005743 ISO
    integral component of membrane GO:0016021 IEA
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Letm1 in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Letm1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Letm1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here