Gene description for Letm1
Gene name	leucine zipper-EF-hand containing transmembrane protein 1
Gene symbol	Letm1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Letm1
ExoCarta	ExoCarta_305457
Vesiclepedia	VP_305457
Entrez Gene	305457
UniProt	Q5XIN6
Letm1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Letm1

Molecular Function     calcium:proton antiporter activity GO:0015369 IBA     calcium:proton antiporter activity GO:0015369 IEA     calcium:proton antiporter activity GO:0015369 ISO     calcium:proton antiporter activity GO:0015369 ISS     ribosome binding GO:0043022 IEA     metal ion binding GO:0046872 IEA Biological Process     calcium ion transport GO:0006816 ISO     mitochondrial calcium ion transmembrane transport GO:0006851 IBA     mitochondrial calcium ion transmembrane transport GO:0006851 ISO     mitochondrial calcium ion transmembrane transport GO:0006851 ISS     mitochondrion organization GO:0007005 IBA     inner mitochondrial membrane organization GO:0007007 ISO     inner mitochondrial membrane organization GO:0007007 ISS     protein hexamerization GO:0034214 IEA     protein hexamerization GO:0034214 ISO     protein hexamerization GO:0034214 ISS     cristae formation GO:0042407 IEA     cristae formation GO:0042407 ISO     protein homooligomerization GO:0051260 IEA     protein homooligomerization GO:0051260 ISO     protein homooligomerization GO:0051260 ISS     mitochondrial calcium ion homeostasis GO:0051560 ISO     mitochondrial calcium ion homeostasis GO:0051560 ISS     negative regulation of mitochondrial calcium ion concentration GO:0051562 IEA     negative regulation of mitochondrial calcium ion concentration GO:0051562 ISO     negative regulation of mitochondrial calcium ion concentration GO:0051562 ISS     calcium export from the mitochondrion GO:0099093 IEA     calcium export from the mitochondrion GO:0099093 ISO     calcium export from the mitochondrion GO:0099093 ISS     mitochondrial potassium ion transmembrane transport GO:0140141 IEA     mitochondrial potassium ion transmembrane transport GO:0140141 ISO     mitochondrial potassium ion transmembrane transport GO:0140141 ISS     regulation of cellular hyperosmotic salinity response GO:1900069 IEA     regulation of cellular hyperosmotic salinity response GO:1900069 ISO     regulation of cellular hyperosmotic salinity response GO:1900069 ISS     proton transmembrane transport GO:1902600 IEA Subcellular Localization     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 ISO     mitochondrial inner membrane GO:0005743 IEA     mitochondrial inner membrane GO:0005743 ISO     mitochondrial inner membrane GO:0005743 ISS