Gene description for Slc25a37
Gene name solute carrier family 25 (mitochondrial iron transporter), member 37
Gene symbol Slc25a37
Other names/aliases Mscp
RGD1359361
Species Rattus norvegicus
 Database cross references - Slc25a37
ExoCarta ExoCarta_306000
Entrez Gene 306000
UniProt Q66H23  
 Slc25a37 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc25a37
Molecular Function
    iron ion transmembrane transporter activity GO:0005381 IEA
Biological Process
    mitochondrial iron ion transport GO:0048250 IEA
    iron ion homeostasis GO:0055072 IEA
    iron ion transmembrane transport GO:0034755 IEA
Subcellular Localization
    mitochondrial inner membrane GO:0005743 IEA
    mitochondrion GO:0005739 ISO
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Slc25a37 in exosomes
1
Experiment ID 90
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSC70|HSP90|TSG101
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc25a37
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc25a37 is involved
PathwayEvidenceSource
Mitochondrial iron-sulfur cluster biogenesis IEA Reactome





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