Gene description for Slc25a37
Gene name solute carrier family 25 (mitochondrial iron transporter), member 37
Gene symbol Slc25a37
Other names/aliases Mscp
RGD1359361
Species Rattus norvegicus
 Database cross references - Slc25a37
ExoCarta ExoCarta_306000
Vesiclepedia VP_306000
Entrez Gene 306000
UniProt Q66H23  
 Slc25a37 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc25a37
Molecular Function
    iron ion transmembrane transporter activity GO:0005381 IEA
    iron ion transmembrane transporter activity GO:0005381 ISO
    ferrous iron transmembrane transporter activity GO:0015093 IBA
    ferrous iron transmembrane transporter activity GO:0015093 ISO
Biological Process
    positive regulation of hemoglobin biosynthetic process GO:0046985 ISO
    positive regulation of hemoglobin biosynthetic process GO:0046985 ISS
    iron import into the mitochondrion GO:0048250 IBA
    iron import into the mitochondrion GO:0048250 IEA
    iron import into the mitochondrion GO:0048250 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    mitochondrial inner membrane GO:0005743 IEA
    mitochondrial inner membrane GO:0005743 ISO
    mitochondrial membrane GO:0031966 IBA
 Experiment description of studies that identified Slc25a37 in sEVs
1
Experiment ID 90
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|HSP90|TSG101|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc25a37
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc25a37 is involved
No pathways found





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