Gene description for Flnb
Gene name filamin B, beta
Gene symbol Flnb
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Flnb
ExoCarta ExoCarta_306204
Entrez Gene 306204
 Flnb identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Flnb
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    actin binding GO:0003779 IEA
    molecular_function GO:0003674 ND
    identical protein binding GO:0042802 ISO
Biological Process
    keratinocyte development GO:0003334 ISO
    cell differentiation GO:0030154 IEA
    epithelial cell morphogenesis GO:0003382 ISO
    biological_process GO:0008150 ND
    actin cytoskeleton organization GO:0030036 ISO
    skeletal muscle tissue development GO:0007519 ISO
Subcellular Localization
    cellular_component GO:0005575 ND
    cytoplasm GO:0005737 ISO
    extracellular exosome GO:0070062 ISO
    plasma membrane GO:0005886 ISO
    focal adhesion GO:0005925 ISO
    stress fiber GO:0001725 ISO
    brush border GO:0005903 ISO
 Experiment description of studies that identified Flnb in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Flnb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Flnb is involved
No pathways found





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