Gene description for Mboat7
Gene name membrane bound O-acyltransferase domain containing 7
Gene symbol Mboat7
Other names/aliases Leng4
RGD1306945
Species Rattus norvegicus
 Database cross references - Mboat7
ExoCarta ExoCarta_308309
Vesiclepedia VP_308309
Entrez Gene 308309
 Mboat7 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Mboat7
Molecular Function
    O-acyltransferase activity GO:0008374 ISO
    lysophospholipid acyltransferase activity GO:0071617 IBA
    lysophospholipid acyltransferase activity GO:0071617 ISO
Biological Process
    phosphatidylinositol biosynthetic process GO:0006661 IBA
    phosphatidylinositol biosynthetic process GO:0006661 ISO
    ventricular system development GO:0021591 ISO
    layer formation in cerebral cortex GO:0021819 ISO
    lipid modification GO:0030258 IBA
    phosphatidylinositol acyl-chain remodeling GO:0036149 ISO
    phosphatidylcholine acyl-chain remodeling GO:0036151 ISO
    phosphatidylinositol metabolic process GO:0046488 ISO
    regulation of triglyceride metabolic process GO:0090207 ISO
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    membrane GO:0016020 IBA
    membrane GO:0016020 ISO
    mitochondria-associated endoplasmic reticulum membrane contact site GO:0044233 IBA
    mitochondria-associated endoplasmic reticulum membrane contact site GO:0044233 ISO
 Experiment description of studies that identified Mboat7 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Mboat7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mboat7 is involved
No pathways found





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