Gene description for Tnpo1
Gene name transportin 1
Gene symbol Tnpo1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Tnpo1
ExoCarta ExoCarta_309126
Vesiclepedia VP_309126
Entrez Gene 309126
 Tnpo1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Tnpo1
Molecular Function
    nuclear localization sequence binding GO:0008139 IBA
    small GTPase binding GO:0031267 IEA
    nuclear import signal receptor activity GO:0061608 IBA
Biological Process
    protein import into nucleus GO:0006606 IBA
    protein import into nucleus GO:0006606 ISO
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified Tnpo1 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Tnpo1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STXBP5L  
Affinity Capture-MS Homo sapiens
2 Ndn  
Affinity Capture-Western Rattus norvegicus
View the network image/svg+xml
 Pathways in which Tnpo1 is involved
No pathways found





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