Gene description for Atl3
Gene name atlastin GTPase 3
Gene symbol Atl3
Other names/aliases RGD1309871
Species Rattus norvegicus
 Database cross references - Atl3
ExoCarta ExoCarta_309187
Vesiclepedia VP_309187
Entrez Gene 309187
UniProt Q0ZHH6  
 Atl3 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Atl3
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 IBA
    GTP binding GO:0005525 IEA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    identical protein binding GO:0042802 ISS
Biological Process
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 ISO
    endoplasmic reticulum organization GO:0007029 IBA
    endoplasmic reticulum organization GO:0007029 IEA
    endoplasmic reticulum organization GO:0007029 ISO
    endoplasmic reticulum organization GO:0007029 ISS
    Golgi organization GO:0007030 IEA
    Golgi organization GO:0007030 ISO
    Golgi organization GO:0007030 ISS
    protein homooligomerization GO:0051260 IBA
    protein homooligomerization GO:0051260 IEA
    protein homooligomerization GO:0051260 ISO
    protein homooligomerization GO:0051260 ISS
    cellular response to type II interferon GO:0071346 IEA
    positive regulation of endoplasmic reticulum tubular network organization GO:1903373 IEA
    positive regulation of endoplasmic reticulum tubular network organization GO:1903373 ISO
    positive regulation of endoplasmic reticulum tubular network organization GO:1903373 ISS
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum GO:0005783 ISS
    membrane GO:0016020 IEA
    membrane GO:0016020 ISO
    membrane GO:0016020 ISS
    endoplasmic reticulum tubular network GO:0071782 ISO
    endoplasmic reticulum tubular network GO:0071782 ISS
    endoplasmic reticulum tubular network membrane GO:0098826 IEA
    endoplasmic reticulum tubular network membrane GO:0098826 ISO
    endoplasmic reticulum tubular network membrane GO:0098826 ISS
 Experiment description of studies that identified Atl3 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Atl3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Atl3 is involved
No pathways found





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