Gene description for Lama2
Gene name laminin, alpha 2
Gene symbol Lama2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Lama2
ExoCarta ExoCarta_309368
Entrez Gene 309368
 Lama2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lama2
Molecular Function
    molecular_function GO:0003674 ND
    receptor binding GO:0005102 IEA
Biological Process
    regulation of embryonic development GO:0045995 IEA
    regulation of cell migration GO:0030334 IEA
    myelination in peripheral nervous system GO:0022011 IEP
    regulation of cell adhesion GO:0030155 IEA
    axon guidance GO:0007411 ISO
    cell adhesion GO:0007155 IEA
    extracellular matrix organization GO:0030198 IEP
    positive regulation of synaptic transmission, cholinergic GO:0032224 ISO
Subcellular Localization
    dendritic spine GO:0043197 IDA
    extracellular exosome GO:0070062 ISO
    basement membrane GO:0005604 ISO
    sarcolemma GO:0042383 ISO
    basal lamina GO:0005605 ISO
 Experiment description of studies that identified Lama2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lama2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lama2 is involved
No pathways found





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