Gene description for Lama2
Gene name laminin, alpha 2
Gene symbol Lama2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Lama2
ExoCarta ExoCarta_309368
Vesiclepedia VP_309368
Entrez Gene 309368
 Lama2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lama2
Molecular Function
    signaling receptor binding GO:0005102 IEA
    extracellular matrix structural constituent GO:0005201 IBA
Biological Process
    cell adhesion GO:0007155 IEA
    axon guidance GO:0007411 IBA
    axon guidance GO:0007411 ISO
    animal organ morphogenesis GO:0009887 IBA
    tissue development GO:0009888 IBA
    Schwann cell differentiation GO:0014037 IEP
    regulation of cell adhesion GO:0030155 IEA
    regulation of cell migration GO:0030334 IEA
    positive regulation of synaptic transmission, cholinergic GO:0032224 ISO
    regulation of embryonic development GO:0045995 IEA
Subcellular Localization
    basement membrane GO:0005604 IBA
    basement membrane GO:0005604 IDA
    basement membrane GO:0005604 ISO
    neuromuscular junction GO:0031594 ISO
    sarcolemma GO:0042383 ISO
    synaptic cleft GO:0043083 ISO
    dendritic spine GO:0043197 IDA
 Experiment description of studies that identified Lama2 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lama2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lama2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here