Gene description for Loxl4
Gene name lysyl oxidase-like 4
Gene symbol Loxl4
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Loxl4
ExoCarta ExoCarta_309380
Entrez Gene 309380
 Loxl4 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Loxl4
Molecular Function
    protein-lysine 6-oxidase activity GO:0004720 ISO
    scavenger receptor activity GO:0005044 IEA
    copper ion binding GO:0005507 IEA
Biological Process
    receptor-mediated endocytosis GO:0006898 IEA
    oxidation-reduction process GO:0055114 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    receptor complex GO:0043235 ISO
    extracellular region GO:0005576 ISO
    membrane GO:0016020 IEA
 Experiment description of studies that identified Loxl4 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Loxl4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Loxl4 is involved
No pathways found





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