Gene description for Abhd17b
Gene name abhydrolase domain containing 17B
Gene symbol Abhd17b
Other names/aliases Cgi67l
Fam108b1
RGD1305246
Species Rattus norvegicus
 Database cross references - Abhd17b
ExoCarta ExoCarta_309399
Vesiclepedia VP_309399
Entrez Gene 309399
UniProt Q6AY17  
 Abhd17b identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Abhd17b
Molecular Function
    palmitoyl-(protein) hydrolase activity GO:0008474 IBA
    palmitoyl-(protein) hydrolase activity GO:0008474 IEA
    palmitoyl-(protein) hydrolase activity GO:0008474 ISO
Biological Process
    protein depalmitoylation GO:0002084 ISO
    macromolecule depalmitoylation GO:0098734 IEA
    regulation of postsynapse organization GO:0099175 IBA
    regulation of postsynapse organization GO:0099175 IDA
    regulation of postsynapse organization GO:0099175 IEP
    regulation of postsynapse organization GO:0099175 IMP
    regulation of protein localization to synapse GO:1902473 IEA
    regulation of protein localization to synapse GO:1902473 ISO
    negative regulation of protein localization to microtubule GO:1902817 IEA
    negative regulation of protein localization to microtubule GO:1902817 ISO
    regulation of dendritic spine maintenance GO:1902950 IEA
    regulation of dendritic spine maintenance GO:1902950 ISO
    positive regulation of protein localization to endosome GO:1905668 IEA
    positive regulation of protein localization to endosome GO:1905668 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    endosome membrane GO:0010008 IBA
    postsynaptic density GO:0014069 ISO
    dendritic spine GO:0043197 IEA
    recycling endosome membrane GO:0055038 IEA
    recycling endosome membrane GO:0055038 ISO
    postsynaptic density membrane GO:0098839 IDA
    postsynaptic density membrane GO:0098839 IEA
    postsynaptic density membrane GO:0098839 IMP
    postsynaptic recycling endosome membrane GO:0098944 IDA
    postsynaptic recycling endosome membrane GO:0098944 IMP
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
 Experiment description of studies that identified Abhd17b in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Abhd17b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here