Gene description for Lama4
Gene name laminin, alpha 4
Gene symbol Lama4
Other names/aliases RGD1560062
Species Rattus norvegicus
 Database cross references - Lama4
ExoCarta ExoCarta_309816
Vesiclepedia VP_309816
Entrez Gene 309816
 Lama4 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lama4
Molecular Function
    signaling receptor binding GO:0005102 IEA
Biological Process
    blood vessel development GO:0001568 ISO
    cell adhesion GO:0007155 IEA
    regulation of cell adhesion GO:0030155 IEA
    regulation of cell migration GO:0030334 IEA
    regulation of embryonic development GO:0045995 IEA
    brown fat cell differentiation GO:0050873 ISO
    negative regulation of cold-induced thermogenesis GO:0120163 ISO
    negative regulation of cold-induced thermogenesis GO:0120163 ISS
Subcellular Localization
    basement membrane GO:0005604 ISO
    neuromuscular junction GO:0031594 ISO
    synaptic cleft GO:0043083 ISO
 Experiment description of studies that identified Lama4 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lama4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lama4 is involved
No pathways found





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